Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Intracranial mass17.11.01.0170.000979%-
Abdominal incarcerated hernia07.16.06.0090.000367%-
Anisocoria06.05.03.013; 17.02.11.0090.000245%-
Anticoagulant-related nephropathy12.03.01.060; 20.05.03.023; 24.07.07.0050.000367%-
Aortic dissection rupture24.02.03.0060.000245%-
Atheroembolism12.02.05.052; 24.01.01.0370.000245%-
Blood loss anaemia01.03.02.018; 24.07.01.0880.007707%-
Cardiac dysfunction02.11.01.0040.000245%-
Carotid arterial embolus17.08.01.067; 24.01.04.0180.000245%-
Catheter site haematoma08.02.02.020; 12.07.02.020; 24.07.01.0900.000245%-
Cerebellar stroke17.08.01.070; 24.04.06.0460.000245%-
Cerebral mass effect17.11.01.0190.001835%-
Cerebral microangiopathy17.08.02.031; 24.03.05.0160.000245%-
Colorectal adenoma07.20.01.019; 16.05.02.0090.000245%-
Dilated cardiomyopathy02.04.01.0170.000734%-
Disease complication08.01.03.0870.000734%-
Eosinophilic granulomatosis with polyangiitis01.02.04.022; 10.02.02.031; 22.01.01.025; 24.12.04.0100.000245%-
Femoral hernia incarcerated07.16.07.0020.000245%-
Gallbladder rupture09.03.02.012; 12.01.17.0050.000734%-
Gastrointestinal angiectasia07.15.04.009; 24.03.03.0480.000245%-
Gastrointestinal vascular malformation haemorrhagic07.15.04.010; 24.07.02.0640.000612%-
Giant cell arteritis06.07.02.010; 10.02.02.032; 17.08.02.033; 24.12.02.0030.000245%-
Haemodynamic rebound08.06.02.024; 24.03.02.0360.000245%-
Haemoperitoneum07.07.02.007; 12.01.17.007; 24.07.02.0650.002569%-
Hepatic vein dilatation09.01.06.028; 24.03.04.0140.000245%-
Iliac artery embolism24.01.02.0140.000245%-
Iliac artery occlusion24.04.03.0160.000245%-
Incarcerated inguinal hernia07.16.02.0050.000489%-
Incarcerated umbilical hernia07.16.03.0040.000245%-
Malignant anorectal neoplasm07.21.05.006; 16.13.01.0210.000245%-
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