Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Encephalomalacia17.11.01.0160.000245%-
Small intestinal haemorrhage07.12.03.002; 24.07.02.0190.001101%
Meningorrhagia12.01.10.016; 17.08.01.056; 24.07.04.0300.000856%-
Neurodegenerative disorder17.02.10.0240.000367%-
Cardiac ventricular thrombosis02.11.01.008; 24.01.05.0060.001101%-
Colon cancer metastatic07.21.01.010; 16.13.01.0120.000245%-
Gastrointestinal mucosal disorder07.11.03.0080.000245%-
Palatal oedema07.05.04.0080.000245%-
Peripheral artery occlusion24.04.03.0220.001223%-
Cardiac perforation02.11.01.006; 12.02.01.0200.001101%-
Multi-organ disorder08.01.03.0740.000367%-
Right ventricular dysfunction02.04.02.0330.000367%
Abdominal compartment syndrome07.11.01.017; 24.04.09.0090.000245%-
Thalamus haemorrhage17.08.01.062; 24.07.04.0330.000734%-
Intracranial haematoma17.08.01.051; 24.07.04.0270.001957%-
Embolic cerebral infarction17.08.01.029; 24.01.04.0090.002691%-
Appendix disorder07.11.01.0200.000245%-
Arterial haemorrhage24.07.01.0630.001590%-
Cardiac myxoma02.10.01.001; 16.02.01.0060.000734%-
Cerebellar haematoma17.08.01.045; 24.07.04.0220.000245%-
Gastric mucosal lesion07.11.03.0070.000367%-
Hernia obstructive08.01.04.0030.000367%-
Facial nerve disorder17.04.03.0060.000245%
Aortic valve disease02.07.03.0020.000538%
Angiodysplasia24.03.03.0170.000856%-
Perforated ulcer08.03.06.0020.000367%-
Gallbladder enlargement09.03.02.0050.000245%-
Thoracic haemorrhage22.02.07.017; 24.07.01.0820.000734%-
Basilar artery thrombosis17.08.01.043; 24.01.04.0140.000489%-
Renal embolism20.01.07.014; 24.01.11.0030.000612%-
The 19th Page    First    Pre   19 20 21 22    Next   Last    Total 22 Pages