Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dabigatran
Drug ID BADD_D00563
Description Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate].
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code B01AE07
DrugBank ID DB14726
KEGG ID D09707
MeSH ID D000069604
PubChem ID 216210
TTD Drug ID D0M7JT
NDC Product Code 51869-0030
UNII I0VM4M70GC
Synonyms Dabigatran | N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine | BIBR 1048 | Pradaxa | Dabigatran Etexilate | Etexilate, Dabigatran | Dabigatran Etexilate Mesylate | Etexilate Mesylate, Dabigatran | Mesylate, Dabigatran Etexilate
Chemical Information
Molecular Formula C25H25N7O3
CAS Registry Number 211914-51-1
SMILES CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Perforation08.01.03.0580.000367%-
Stenosis08.01.03.0600.000245%-
Multiple organ dysfunction syndrome08.01.03.0570.011866%
Device related thrombosis08.07.05.001; 24.01.01.0270.000856%-
Adenocarcinoma of colon07.21.01.008; 16.13.01.0100.000367%-
Antiphospholipid syndrome01.01.02.016; 10.04.01.009; 18.02.04.002; 24.01.01.0290.000979%-
Arterial rupture12.01.11.010; 24.03.02.0270.000489%-
Bladder cancer recurrent16.08.01.003; 20.03.04.0050.000367%-
Bladder obstruction20.03.01.0120.000367%-
Bleeding varicose vein24.10.04.0020.001076%-
Brain neoplasm malignant16.30.04.002; 17.20.04.0020.000367%-
Bronchial carcinoma16.19.02.004; 22.08.01.0150.000367%-
Cardiac failure chronic02.05.01.0090.000856%-
Cerebellar haemorrhage17.08.01.046; 24.07.04.0230.001957%-
Cerebral artery thrombosis17.08.01.026; 24.01.04.0080.000979%-
Cholangitis acute09.02.01.0060.000612%-
Coronary artery embolism02.02.01.013; 24.01.05.0070.000489%-
Diverticulum intestinal haemorrhagic07.10.01.003; 24.07.02.0430.002080%-
Exsanguination24.07.01.0660.000612%-
Extravasation blood24.07.01.0670.000367%-
Gastrointestinal angiodysplasia07.15.04.001; 24.03.03.0070.000489%-
Haemorrhagic cerebral infarction17.08.01.050; 24.07.04.0260.000979%-
Haemorrhagic infarction24.04.02.0080.001101%-
Hemianopia homonymous06.02.07.007; 17.17.01.0240.000856%-
Hepatic haematoma09.01.06.016; 12.01.17.008; 24.07.01.0710.000489%-
Hilar lymphadenopathy01.09.01.023; 22.09.03.0050.000245%-
Incarcerated hernia08.01.04.0040.001713%-
Intracranial tumour haemorrhage16.32.03.023; 17.08.01.052; 24.07.04.0280.000245%-
Jugular vein thrombosis24.01.02.0070.000367%-
Lung carcinoma cell type unspecified stage IV16.19.02.006; 22.08.01.0190.000245%-
The 17th Page    First    Pre   17 18 19 20 21    Next   Last    Total 22 Pages