Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cortisone acetate
Drug ID BADD_D00533
Description Cortisone acetate was first isolate in 1935 and became more widely researched in 1949.[A226295] Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203] Cortisone acetate was granted FDA approval on 13 June 1950.[L15107]
Indications and Usage Cortisone acetate is indicated to treat a wide variety of endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203]
Marketing Status approved; investigational
ATC Code H02AB10; S01BA03
DrugBank ID DB01380
KEGG ID D00973
MeSH ID D003348
PubChem ID 5745
TTD Drug ID D0X4RS
NDC Product Code 62135-173; 0220-1554; 64958-0025; 82298-129
UNII 883WKN7W8X
Synonyms Cortisone | Cortisone Acetate | 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate | Cortone Acetate | Adreson
Chemical Information
Molecular Formula C23H30O6
CAS Registry Number 50-04-4
SMILES CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)CCC34C)C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Alkalosis hypokalaemic14.01.02.002---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001--
Asthma10.01.03.010; 22.03.01.002---
Back pain15.03.04.005--
Carbohydrate tolerance decreased13.02.02.003---
Cardiac failure congestive02.05.01.002---
Cataract subcapsular06.06.01.002---
Coma17.02.09.001---
Condition aggravated08.01.03.004--
Confusional state17.02.03.005; 19.13.01.001-
Cough22.02.03.001-
Crohn's disease07.08.01.015; 10.02.01.005--
Depression19.15.01.001-
Dermatitis allergic10.01.03.014; 23.03.04.003---
Diabetes mellitus05.06.01.001; 14.06.01.001---
Diarrhoea07.02.01.001-
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Drug hypersensitivity10.01.01.001--
Drug ineffective08.06.01.006--
Dyspnoea02.11.05.003; 22.02.01.004--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002---
Erythema23.03.06.001--
Euphoric mood19.04.02.006-
Exophthalmos05.02.02.002; 06.09.04.001---
Fatigue08.01.01.002--
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