| Pharmaceutical Information |
| Drug Name |
Codeine sulfate |
| Drug ID |
BADD_D00517 |
| Description |
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory functions. Opiates such as codeine are derived from the poppy plant, _Papaver somniferum_ (Papaveraceae).[A175096]
Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.[LABEL,A175096] |
| Indications and Usage |
Codeine sulfate is a form of this drug that is commonly used. It is available in tablet form [FDA label] and indicated for the relief of mild to moderately severe pain, where the use of an opioid analgesic is appropriate [FDA label].
The solution form is used by itself or combined in a syrup with other drugs and is used as a cough suppressant in adults aged 18 and above [L5521], [L5524]. |
| Marketing Status |
approved; illicit |
| ATC Code |
R05DA04 |
| DrugBank ID |
DB00318
|
| KEGG ID |
D03580
|
| MeSH ID |
D003061
|
| PubChem ID |
5359613
|
| TTD Drug ID |
D03DIG
|
| NDC Product Code |
0054-0243; 0054-0244; 0527-1698; 0054-0245; 0406-1580; 0527-1699 |
| UNII |
11QV9BS0CB
|
| Synonyms |
Codeine | Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)- | N-Methylmorphine | N Methylmorphine | Isocodeine | Codeine Phosphate | Ardinex |
|
| Chemical Information |
| Molecular Formula |
C36H44N2O10S |
| CAS Registry Number |
1420-53-7 |
| SMILES |
CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C=C4)O.CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C
=C4)O.OS(=O)(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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