Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cloxacillin
Drug ID BADD_D00510
Description A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin].
Indications and Usage Cloxacillin is indicated for the treatment of beta-hemolytic streptococcal, pneumococcal, and staphylococcal infections (including beta-lactamase producing organisms).[L33170]
Marketing Status approved; investigational; vet_approved
ATC Code J01CF02
DrugBank ID DB01147
KEGG ID D07733
MeSH ID D003023
PubChem ID 6098
TTD Drug ID D04KTZ
NDC Product Code Not Available
UNII O6X5QGC2VB
Synonyms Cloxacillin | Chloroxacillin | Syntarpen | Tegopen | Cloxacillin Sodium | Sodium, Cloxacillin | Sodium Cloxacillin | Cloxacillin, Sodium
Chemical Information
Molecular Formula C19H18ClN3O5S
CAS Registry Number 61-72-3
SMILES CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Haematuria20.02.01.006; 21.10.01.018; 24.07.01.047--
Haemolytic anaemia01.06.03.002---
Hepatitis09.01.07.004---
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Injection site reaction08.02.03.014; 12.07.03.015--
Jaundice01.06.04.004; 09.01.01.004; 23.03.03.030---
Jaundice cholestatic09.01.01.005---
Leukopenia01.02.02.001---
Lip swelling07.05.04.005; 10.01.05.005; 23.04.01.007---
Myalgia15.05.02.001--
Mydriasis06.05.03.004; 17.02.11.003---
Nausea07.01.07.001--
Nephritis20.05.02.001---
Neutropenia01.02.03.004---
Oedema08.01.07.006; 14.05.06.010---
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.011--
Oral candidiasis07.05.07.001; 11.03.03.004---
Pallor08.01.03.032; 23.03.03.031; 24.03.04.001---
Paraesthesia17.02.06.005; 23.03.03.094--
Periorbital oedema06.08.03.017; 10.01.05.010; 23.04.01.002--
Petechiae01.01.03.002; 23.06.01.003; 24.07.06.004---
Phlebitis12.02.01.002; 24.12.03.004--
Pruritus23.03.12.001--
Pseudomembranous colitis07.19.01.003; 11.02.02.002---
Purpura01.01.04.003; 23.06.01.004; 24.07.06.005--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Rash erythematous23.03.13.029---
Rash macular23.03.13.003---
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