Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Clobetasol
Drug ID BADD_D00489
Description Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
Indications and Usage Not Available
Marketing Status approved; experimental; investigational
ATC Code D07AD01
DrugBank ID DB11750
KEGG ID D07715
MeSH ID D002990
PubChem ID 5311051
TTD Drug ID D0FL5V
NDC Product Code Not Available
UNII ADN79D536H
Synonyms Clobetasol | Clofenazon | Clobetasol Propionate | Clobetasol 17-Propionate | Clobetasol 17 Propionate | Clobex | Cormax | OLUX | Dermovate | Embeline | Embeline E | Temovate
Chemical Information
Molecular Formula C22H28ClFO4
CAS Registry Number 25122-41-2
SMILES CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Application site atrophy08.02.01.037; 12.07.01.037---
Application site irritation08.02.01.003; 12.07.01.003---
Application site pain08.02.01.004; 12.07.01.004---
Application site pruritus08.02.01.005; 12.07.01.005; 23.03.12.004---
Application site reaction08.02.01.006; 12.07.01.006---
Atopy10.01.04.005---
Burning sensation08.01.09.029; 17.02.06.001---
Cushing's syndrome05.01.01.001; 14.11.01.007; 19.07.03.002; 24.08.04.001---
Dermatitis23.03.04.002---
Dermatitis acneiform23.02.01.004--
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.004---
Discomfort08.01.08.003---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry skin23.03.03.001--
Endocrine disorder05.09.01.001---
Erythema23.03.06.001---
Eye irritation06.04.05.003---
Eye pain06.08.03.002--
Folliculitis11.02.01.053; 23.11.04.003--
Glycosuria20.02.01.005--
Hair colour changes23.02.06.001--
Headache17.14.01.001--
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hypertrichosis23.02.04.002--
Hypoaesthesia17.02.06.023; 23.03.03.081---
Infection11.01.08.002---
Influenza11.05.03.001; 22.07.02.001---
Instillation site pain08.02.01.008; 12.07.01.008---
Leukoderma23.05.02.001---
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