Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Citric acid
Drug ID BADD_D00477
Description A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability. Citric acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120]
Indications and Usage Not Available
Marketing Status approved; nutraceutical; vet_approved
ATC Code A09AB04
DrugBank ID DB04272
KEGG ID D01222
MeSH ID D019343
PubChem ID 311
TTD Drug ID D02RTS
NDC Product Code 81803-040
UNII XF417D3PSL
Synonyms Citric Acid | Citric Acid Monohydrate | Uralyt U | Citrate | Citric Acid, Anhydrous | Anhydrous Citric Acid
Chemical Information
Molecular Formula C6H8O7
CAS Registry Number 77-92-9
SMILES C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Muscle twitching15.05.03.0050.004128%-
Nausea07.01.07.0011.839044%
Neck pain15.03.04.0090.148070%
Pallor08.01.03.032; 23.03.03.031; 24.03.04.0011.693163%-
Palpitations02.11.04.0120.167017%
Paraesthesia17.02.06.005; 23.03.03.0943.654477%
Peripheral coldness08.01.09.010; 23.06.04.008; 24.04.03.0060.005820%-
Restlessness17.02.05.021; 19.11.02.0020.360701%
Tachypnoea22.02.01.0140.003220%-
Tetany05.04.02.003; 14.04.01.005; 15.05.03.0130.024190%-
Thirst08.01.09.021; 14.03.02.0070.901050%-
Vision blurred06.02.06.007; 17.17.01.0100.779647%
Vomiting07.01.07.003--
Muscle tightness15.05.03.0070.004417%-
Citrate toxicity12.03.01.043; 14.11.01.026---
Epigastric discomfort07.01.02.0040.001610%-
Hypoaesthesia oral07.05.05.003; 17.02.06.0210.007430%-
Paraesthesia oral07.05.05.035; 17.02.06.0080.010939%-
Poisoning12.03.01.004---
Muscle contracture15.03.05.0240.000413%-
Vessel puncture site haematoma08.02.04.002; 12.07.04.003; 24.07.01.0180.001404%-
Gastrointestinal tract irritation07.08.03.008---
Pharyngeal swelling22.04.05.0280.000908%-
Vessel puncture site erythema08.02.04.036; 12.07.04.036; 23.03.06.0290.001404%-
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