Pharmaceutical Information |
Drug Name |
Cidofovir |
Drug ID |
BADD_D00463 |
Description |
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223] |
Indications and Usage |
For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) |
Marketing Status |
approved |
ATC Code |
J05AB12 |
DrugBank ID |
DB00369
|
KEGG ID |
D00273
|
MeSH ID |
D000077404
|
PubChem ID |
60613
|
TTD Drug ID |
D04AAW
|
NDC Product Code |
48954-728 |
UNII |
JIL713Q00N
|
Synonyms |
Cidofovir | HPMPC | GS 504 | GS-504 | GS504 | Cidofovir, Sodium Salt | Cidofovir Sodium | Cidofovir, (R)-isomer | Cidofovir Anhydrous | 1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine | 1-((3-Hydroxy-2-phosphonylmethoxy)propyl)cytosine | Vistide | Cidofovir, (+-)-isomer |
|
Chemical Information |
Molecular Formula |
C8H14N3O6P |
CAS Registry Number |
113852-37-2 |
SMILES |
C1=CN(C(=O)N=C1N)CC(CO)OCP(=O)(O)O |
Chemical Structure |
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ADRs Induced by Drug |
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