Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cidofovir
Drug ID BADD_D00463
Description Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223]
Indications and Usage For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS)
Marketing Status Prescription; Discontinued
ATC Code J05AB12
DrugBank ID DB00369
KEGG ID C06909
MeSH ID D000077404
PubChem ID 60613
TTD Drug ID D04AAW
NDC Product Code 48954-728
Synonyms Cidofovir | HPMPC | GS 504 | GS-504 | GS504 | Cidofovir, Sodium Salt | Cidofovir Sodium | Cidofovir, (R)-isomer | Cidofovir Anhydrous | 1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine | 1-((3-Hydroxy-2-phosphonylmethoxy)propyl)cytosine | Vistide | Cidofovir, (+-)-isomer
Chemical Information
Molecular Formula C8H14N3O6P
CAS Registry Number 113852-37-2
SMILES C1=CN(C(=O)N=C1N)CC(CO)OCP(=O)(O)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Protein urine present13.13.02.006--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Disturbance in sexual arousal19.08.04.003--Not Available
Angiopathy24.03.02.007--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Urine output increased13.13.03.002--Not Available
Mediastinal disorder22.09.03.001--Not Available
Decreased appetite08.01.09.028; 14.03.01.005--
Ill-defined disorder08.01.03.049--Not Available
Inner ear disorder04.04.02.002--Not Available
Blood disorder01.05.01.004--Not Available
Hyperlipidaemia14.08.03.001--
Urethritis noninfective20.07.02.002--Not Available
Device occlusion27.01.02.003--Not Available
Liver injury09.01.07.022; 12.01.02.003--Not Available
Acute kidney injury20.01.03.016--
Candida infection11.03.03.021--
Anal incontinence07.01.06.029; 17.05.01.021--
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ADReCS-Target
Drug Name ADR Term Target
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