| Pharmaceutical Information |
| Drug Name |
Chlorothiazide |
| Drug ID |
BADD_D00442 |
| Description |
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812) |
| Indications and Usage |
Chlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. |
| Marketing Status |
approved; vet_approved |
| ATC Code |
C03AA04 |
| DrugBank ID |
DB00880
|
| KEGG ID |
D00519
|
| MeSH ID |
D002740
|
| PubChem ID |
2720
|
| TTD Drug ID |
D0M9WM
|
| NDC Product Code |
42419-007; 12828-0005; 38779-3147; 33656-0012; 65649-311; 59605-1745; 57821-001 |
| UNII |
77W477J15H
|
| Synonyms |
Chlorothiazide |
|
| Chemical Information |
| Molecular Formula |
C7H6ClN3O4S2 |
| CAS Registry Number |
58-94-6 |
| SMILES |
C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2 |
| Chemical Structure |
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Renal impairment | 20.01.03.010 | - | - | - |
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