Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cefuroxime sodium
Drug ID BADD_D00409
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status approved
ATC Code S01AA27; J01DC02
DrugBank ID DB01112
KEGG ID D00915
MeSH ID D002444
PubChem ID 23670318
TTD Drug ID D0Y2IE
NDC Product Code 25021-183; 52946-0905; 25021-118; 25021-182; 25021-119
UNII R8A7M9MY61
Synonyms Cefuroxime | Cephuroxime | Zinacef | Ketocef
Chemical Information
Molecular Formula C16H15N4NaO8S
CAS Registry Number 56238-63-2
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)[O-].[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001---
Alanine aminotransferase increased13.03.04.005--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Aplastic anaemia01.03.03.002---
Aspartate aminotransferase increased13.03.04.011--
Blood bilirubin increased13.03.04.018--
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood urea increased13.13.01.006---
Cholestasis09.01.01.001---
Colitis07.08.01.001--
Creatinine renal clearance decreased13.13.01.013---
Cutaneous vasculitis10.02.02.003; 23.06.02.001; 24.12.04.008---
Diarrhoea07.02.01.001--
Eosinophilia01.02.04.001--
Erythema multiforme10.01.03.015; 23.03.01.003--
Haematocrit decreased13.01.05.001---
Haemoglobin decreased13.01.05.003---
Haemolytic anaemia01.06.03.002---
Leukopenia01.02.02.001---
Nausea07.01.07.001--
Nephropathy toxic12.03.01.010; 20.05.03.002---
Neutropenia01.02.03.004---
Pancytopenia01.03.03.003---
Prothrombin time prolonged13.01.02.012---
Pruritus23.03.12.001--
Pseudomembranous colitis07.19.01.003; 11.02.02.002---
Pyrexia08.05.02.003--
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