Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefuroxime
Drug ID BADD_D00407
Description Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Indications and Usage For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.
Marketing Status approved
ATC Code J01DC02; S01AA27
DrugBank ID DB01112
KEGG ID D00262
MeSH ID D002444
PubChem ID 41375
TTD Drug ID D0Y2IE
NDC Product Code 0143-9567; 0143-9569; 0143-9976; 0143-9568; 0143-9977; 0143-9979
UNII O1R9FJ93ED
Synonyms Cefuroxime | Cephuroxime | Zinacef | Ketocef
Chemical Information
Molecular Formula C16H16N4O8S
CAS Registry Number 55268-75-2
SMILES CON=C(C1=CC=CO1)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Stress cardiomyopathy02.04.01.012; 24.04.04.0260.000215%-
Foetal hypokinesia18.03.02.0150.000286%-
Subretinal fluid06.09.03.027; 12.01.04.0310.000215%-
Cutaneous symptom23.07.04.0230.000215%-
Macular detachment06.09.03.0200.002003%-
Fine motor skill dysfunction17.01.02.0200.000143%-
Cross sensitivity reaction10.01.01.0360.000787%-
Delayed dark adaptation06.02.06.0210.001216%-
Dyschromatopsia06.02.09.0030.000143%-
Dyskinesia neonatal17.01.02.029; 18.04.04.0140.000143%-
Gait inability08.01.02.011; 17.02.05.069---
Haemophagocytic lymphohistiocytosis01.05.01.026; 10.02.01.077; 16.32.03.0380.000143%-
Larynx irritation22.04.01.0150.000143%-
Neonatal dyspnoea02.11.05.008; 18.04.09.012; 22.11.01.0120.000143%-
Periorbital fat herniation06.08.03.0300.000143%-
Pulmonary necrosis22.01.02.0350.000143%-
Retinal drusen06.09.03.0340.000143%-
Serous retinal detachment06.09.03.0370.001216%-
Symmetrical drug-related intertriginous and flexural exanthema10.01.01.046; 23.03.05.0120.000386%-
Taste disorder07.14.03.004; 17.02.07.0290.000386%-
Vulvovaginal inflammation21.14.02.014---
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ADReCS-Target
Drug Name ADR Term Target
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