Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ceftibuten dihydrate
Drug ID BADD_D00401
Description Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Indications and Usage Indicated for the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Marketing Status approved; investigational
ATC Code J01DD14
DrugBank ID DB01415
KEGG ID D02121
MeSH ID D000077722
PubChem ID 5282241
TTD Drug ID D05JDR
NDC Product Code Not Available
UNII 62F4443RWP
Synonyms Ceftibuten | 7-(2-(2-amino-4-thiazolyl)-4-carboxy-2-butenoylamino)-3-cephem-4-carboxylic acid | 7432 S | 7432-S | SCH 39720 | SCH39720 | SCH-39720 | Cedax
Chemical Information
Molecular Formula C15H18N4O8S2
CAS Registry Number 118081-34-8
SMILES C1C=C(N2C(S1)C(C2=O)NC(=O)C(=CCC(=O)O)C3=CSC(=N3)N)C(=O)O.O.O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation17.02.05.012; 19.06.02.001--
Agranulocytosis01.02.03.001---
Alanine aminotransferase increased13.03.04.005--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Aphasia17.02.03.001; 19.21.01.001--
Aplastic anaemia01.03.03.002---
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001---
Blood bilirubin increased13.03.04.018--
Blood creatinine increased13.13.01.004--
Blood urea increased13.13.01.006---
Body temperature increased13.15.01.001---
Chills08.01.09.001; 15.05.03.016--
Cholestasis09.01.01.001---
Constipation07.02.02.001--
Dehydration14.05.05.001--
Dermatitis23.03.04.002---
Dermatitis diaper21.10.01.016; 23.03.04.005---
Diarrhoea07.02.01.001--
Disability26.01.01.003---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Dysuria20.02.02.002--
Eosinophil count increased13.01.06.004---
Eructation07.01.02.003--
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