Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cefpodoxime
Drug ID BADD_D00395
Description Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Indications and Usage Indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms.
Marketing Status approved; vet_approved
ATC Code J01DD13
DrugBank ID DB01416
KEGG ID D07650
MeSH ID C053268
PubChem ID 6335986
TTD Drug ID D0W6CA
NDC Product Code Not Available
UNII 7R4F94TVGY
Synonyms cefpodoxime | U 76253A | U-76,253A | RU 51746 | RU-51746 | R 3746 | R-3746 | R 3763 | R-3763
Chemical Information
Molecular Formula C15H17N5O6S2
CAS Registry Number 80210-62-4
SMILES COCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Prothrombin level increased13.01.02.011---
Pruritus23.03.12.001--
Pseudomembranous colitis07.19.01.003; 11.02.02.002---
Rash23.03.13.001---
Rash maculo-papular23.03.13.004--
Rash pustular11.01.12.002; 23.03.10.003--
Rectal haemorrhage07.12.03.001; 24.07.02.018--
Renal failure20.01.03.005---
Rhinitis11.01.13.004; 22.07.03.006--
Seizure17.12.03.001--
Serum sickness10.01.03.004; 12.02.08.004--
Serum sickness-like reaction08.01.03.003; 10.01.03.005---
Shock24.06.02.002---
Sinusitis11.01.13.005; 22.07.03.007--
Skin exfoliation23.03.07.003---
Somnolence17.02.04.006; 19.02.05.003--
Stevens-Johnson syndrome10.01.01.045; 11.07.01.005; 12.03.01.014; 23.03.01.007--
Stomatitis07.05.06.005--
Sunburn12.05.02.001; 23.03.09.007---
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tension19.06.02.005---
Thirst08.01.09.021; 14.03.02.007---
Thrombocytopenia01.08.01.002---
Thrombocytopenic purpura01.08.01.003; 23.06.01.007---
Thrombocytosis01.08.02.001---
Tinnitus04.04.01.002; 17.04.07.004--
Tongue disorder07.14.01.002---
Tooth disorder07.09.05.001---
Toothache07.09.06.001--
Toxic epidermal necrolysis10.01.01.006; 11.07.01.006; 12.03.01.015; 23.03.01.008--
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