Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cefoxitin sodium
Drug ID BADD_D00394
Description Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Indications and Usage For the treatment of serious infections caused by susceptible strains microorganisms.
Marketing Status approved
ATC Code J01DC01
DrugBank ID DB01331
KEGG ID D00913
MeSH ID D002440
PubChem ID 23667300
TTD Drug ID D02VFC
NDC Product Code 63323-342; 63323-341; 52946-0828; 0264-3123; 0264-3125
UNII Q68050H03T
Synonyms Cefoxitin | MK-306 | MK 306 | MK306 | Cefoxitin Sodium | Sodium, Cefoxitin | Mefoxin | Méfoxin | Mefoxitin
Chemical Information
Molecular Formula C16H16N3NaO7S2
CAS Registry Number 33564-30-6
SMILES COC1(C2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)[O-])NC(=O)CC3=CC=CS3.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Prothrombin time prolonged13.01.02.012---
Pruritus23.03.12.001--
Pseudomembranous colitis07.19.01.003; 11.02.02.002---
Pyrexia08.05.02.003--
Rash23.03.13.001---
Seizure17.12.03.001--
Serum sickness-like reaction08.01.03.003; 10.01.03.005---
Stevens-Johnson syndrome10.01.01.045; 11.07.01.005; 12.03.01.014; 23.03.01.007--
Superinfection11.01.08.009---
Thrombocytopenia01.08.01.002---
Thrombophlebitis24.01.02.001---
Urine glucose false positive13.02.02.006---
Urticaria10.01.06.001; 23.04.02.001--
Vaginal infection11.01.10.002; 21.14.02.002--
Vomiting07.01.07.003--
Vulvovaginal candidiasis11.03.03.005; 21.14.02.003---
Tubulointerstitial nephritis20.05.02.002---
Haemorrhage24.07.01.002---
Blood alkaline phosphatase increased13.04.02.004--
Coombs test positive13.01.01.002---
Renal impairment20.01.03.010---
Bone marrow failure01.03.03.005--
Acute kidney injury20.01.03.016--
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