| Pharmaceutical Information |
| Drug Name |
Cefazolin |
| Drug ID |
BADD_D00382 |
| Description |
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine. |
| Indications and Usage |
Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylaxis; if required metronidazole may be added to cover B. fragilis. |
| Marketing Status |
approved |
| ATC Code |
J01DB04 |
| DrugBank ID |
DB01327
|
| KEGG ID |
D02299
|
| MeSH ID |
D002437
|
| PubChem ID |
33255
|
| TTD Drug ID |
D09KDN
|
| NDC Product Code |
0409-2585; 0143-9923; 0781-3451; 0404-9833; 72572-055; 60505-6231; 0781-3450; 60505-6142; 60505-6143; 71872-7027; 44567-707; 44567-840; 52584-924; 71205-679; 72572-056; 60505-6243; 17337-0300; 0143-9924; 44567-120; 52584-087; 60505-6244; 67184-0560; 67184-1001; 0404-9835; 44567-706; 52584-923; 70518-3047; 0143-9262; 0404-9834; 71872-7141; 0781-3452; 0143-9139; 0143-9140; 0143-9261; 0143-9665; 0143-9983; 44567-708 |
| UNII |
IHS69L0Y4T
|
| Synonyms |
Cefazolin | Cephazolin | Cefamedin | Cefamezine | Cephamezine | Gramaxin | Kefzol | Totacef | Ancef | Cefazolin Sodium | Sodium, Cefazolin | Sodium Cephazolin | Cephazolin, Sodium | Cephazolin Sodium | Sodium, Cephazolin |
|
| Chemical Information |
| Molecular Formula |
C14H14N8O4S3 |
| CAS Registry Number |
25953-19-9 |
| SMILES |
CC1=NN=C(S1)SCC2=C(N3C(C(C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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