Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cefadroxil monohydrate
Drug ID BADD_D00381
Description Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Indications and Usage For the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenes
Marketing Status approved; vet_approved; withdrawn
ATC Code J01DB05
DrugBank ID DB01140
KEGG ID D02353
MeSH ID D002434
PubChem ID 47964
TTD Drug ID D0X9ZC
NDC Product Code 61303-111; 61303-715; 52946-0903
UNII 280111G160
Synonyms Cefadroxil | Cephadroxyl | Cefadroxil Anhydrous | 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6R-(6alpha,7beta(R*)))- | Ultracef | Bidocef | Duricef | BL-S 578 | BL S 578 | BLS 578 | BL-S578 | BL S578 | BLS578 | S-578 | S 578 | S578 | 4-Hydroxycephalexin | 4 Hydroxycephalexin | Cefadroxil Monohydrate
Chemical Information
Molecular Formula C16H19N3O6S
CAS Registry Number 66592-87-8
SMILES CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)SC1)C(=O)O.O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001---
Alanine aminotransferase increased13.03.04.005--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Aplastic anaemia01.03.03.002---
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.04.011--
Blood bilirubin increased13.03.04.018--
Blood creatinine increased13.13.01.004--
Blood lactate dehydrogenase increased13.04.02.002--
Blood urea increased13.13.01.006---
Cholestasis09.01.01.001---
Diarrhoea07.02.01.001--
Dyspepsia07.01.02.001--
Eosinophilia01.02.04.001--
Erythema multiforme10.01.03.015; 23.03.01.003--
Genital candidiasis11.03.03.002; 21.10.03.001---
Haemolytic anaemia01.06.03.002---
Hepatic failure09.01.03.002--
Hepatic function abnormal09.01.02.001---
Hypersensitivity10.01.03.003--
Nausea07.01.07.001--
Nephropathy toxic12.03.01.010; 20.05.03.002---
Neutropenia01.02.03.004---
Pancytopenia01.03.03.003---
Prothrombin time prolonged13.01.02.012---
Pruritus genital21.10.01.002; 23.03.12.008---
Pseudomembranous colitis07.19.01.003; 11.02.02.002---
Pyrexia08.05.02.003--
Serum sickness10.01.03.004; 12.02.08.004--
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