| Pharmaceutical Information |
| Drug Name |
Caspofungin acetate |
| Drug ID |
BADD_D00377 |
| Description |
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. |
| Indications and Usage |
For the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies. |
| Marketing Status |
approved |
| ATC Code |
J02AX04 |
| DrugBank ID |
DB00520
|
| KEGG ID |
D02501
|
| MeSH ID |
D000077336
|
| PubChem ID |
6850808
|
| TTD Drug ID |
D00ZCN
|
| NDC Product Code |
70860-107; 72266-106; 72843-434; 14474-037; 69806-0092; 63323-358; 70860-106; 72266-107; 25021-195; 72611-700; 52076-6230; 0006-3823; 72611-702; 72843-533; 69766-064; 68083-158; 0781-3423; 57884-0030; 68083-159; 0781-3421; 62227-022; 25021-194; 63323-356; 0006-3822 |
| UNII |
VUW370O5QE
|
| Synonyms |
Caspofungin | Cancidas | MK 0991 | MK-0991 | MK0991 | Caspofungin MSD | L 743,872 | L-743,872 | L743,872 | L-743872 | L743872 | L 743872 | Caspofungin Acetate |
|
| Chemical Information |
| Molecular Formula |
C56H96N10O19 |
| CAS Registry Number |
179463-17-3 |
| SMILES |
CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(C(NC(=O)C2C(CCN2C(=O)C(NC(=O)C(NC(=O)C3CC(CN3C(=O)
C(NC1=O)C(C)O)O)C(C(C4=CC=C(C=C4)O)O)O)C(CCN)O)O)NCCN)O.CC(=O)O.CC(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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