ADReCS

Pharmaceutical Information

Drug Name	Carbamazepine
Drug ID	BADD_D00356
Description	Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.[L1335] Interestingly, carbamazepine was the first anticonvulsant used to treat individuals with bipolar disorder.[A180319]
Indications and Usage	For the treatment of epilepsy and pain associated with true trigeminal neuralgia.
Marketing Status	Prescription; Discontinued
ATC Code	N03AF01
DrugBank ID	DB00564
KEGG ID	D00252
MeSH ID	D002220
PubChem ID	2554
TTD Drug ID	D04MSM
NDC Product Code	60687-594; 51672-4123; 70518-3174; 67296-1637; 0781-5988; 68094-008; 0078-0509; 16571-682; 68084-561; 50090-5740; 68084-562; 0121-1894; 75834-221; 63629-8753; 70518-0181; 0904-7116; 68788-7825; 71335-0461; 51672-4047; 60505-2807; 60429-032; 50090-0384; 68071-4313; 0904-6172; 48087-0051; 70518-1769; 75834-220; 70518-2456; 68382-555; 42419-014; 29033-004; 30698-421; 16571-681; 16714-063; 0781-5987; 38779-0114; 50268-171; 70518-1433; 72189-157; 51927-2176; 54092-172; 13668-268; 51672-4124; 71930-072; 51552-0653; 70518-3176; 54092-173; 0615-3505; 0078-0508; 51672-4149; 35561-355; 65344-0028; 70518-1545; 0093-0090; 16714-065; 68382-557; 43063-328; 68788-7210; 0078-0512; 71930-073; 70518-3335; 68382-556; 71335-1730; 29033-019; 67386-621; 70518-3146; 70518-1436; 0781-8016; 51407-215; 49452-1705; 0832-6023; 43353-953; 70518-3266; 16714-064; 55154-1396; 76003-0251; 0078-0511; 0615-8125; 66993-409; 60505-2805; 60429-934; 51672-4150; 0093-0778; 17856-0407; 72664-218; 66993-407; 70518-2426; 51672-4151; 0832-6024; 63629-8255; 50090-2161; 70771-1469; 62512-0024; 70966-0020; 68094-007; 16571-680; 70518-2489; 60687-479; 70771-1470; 71205-025; 48087-0052; 35561-357; 51672-4005; 0121-1724; 13668-271; 60432-129; 71610-336; 60687-583; 63629-8743; 0121-0947; 70518-2841; 62991-1027; 35561-356; 0093-0109; 30698-419; 0904-6885; 70518-2653; 71930-074; 63552-060; 50090-4443; 63629-8721; 65372-1102; 71335-0691; 66993-408; 54092-171; 70771-1468; 63629-8720; 70518-2242; 0832-6022; 60505-0183; 60505-2806; 58118-0268; 0078-0510; 63629-8715; 51672-4041; 71335-0462; 50268-170; 29033-020; 0121-0862; 70518-0902; 50268-172; 0904-3854; 51672-4125; 30698-423
Synonyms	Carbamazepine \| Carbamazepine Acetate \| Carbamazepine Dihydrate \| Carbamazepine Hydrochloride \| Carbamazepine L-Tartrate (4:1) \| Carbamazepine Anhydrous \| Carbamazepine Sulfate (2:1) \| Carbazepin \| Epitol \| Finlepsin \| Neurotol \| Tegretol \| Amizepine \| Carbamazepine Phosphate

Chemical Information

Molecular Formula	C15H12N2O
CAS Registry Number	298-46-4
SMILES	C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N
Chemical Structure

ADRs Induced by Drug

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Bronchitis	11.01.09.001; 22.07.01.001	-	-
Bundle branch block right	02.03.01.011	0.004210%		Not Available
Burning sensation	08.01.09.029; 17.02.06.001	-	-	Not Available
C-reactive protein increased	13.09.01.007	0.009261%		Not Available
Cardiac arrest	02.03.04.001	0.003075%
Cardiac failure	02.05.01.001	-	-
Cardiac failure acute	02.05.01.005	0.000329%		Not Available
Cardiac failure congestive	02.05.01.002	-	-	Not Available
Cardiac murmur	13.14.01.001	0.001263%		Not Available
Cardio-respiratory arrest	02.03.04.002; 22.02.06.007	0.001867%		Not Available
Cardiomegaly	02.04.02.001	0.001684%		Not Available
Cardiomyopathy	02.04.01.001	0.002526%		Not Available
Cataract	06.06.01.001	-	-
Catatonia	19.11.01.001	0.001684%		Not Available
Cellulitis	11.02.01.001; 23.09.01.001	-	-	Not Available
Cellulitis staphylococcal	11.02.05.006; 23.09.01.013	0.001684%		Not Available
Cerebellar ataxia	08.01.02.006; 17.02.02.013	0.000842%		Not Available
Cerebellar syndrome	17.02.02.002	0.004631%		Not Available
Cerebral haemorrhage	17.08.01.003; 24.07.04.001	-	-	Not Available
Cerebral infarction	17.08.01.004; 24.04.06.002	-	-	Not Available
Cerebral ischaemia	17.08.01.005; 24.04.06.003	0.000329%
Cerebral palsy	03.10.03.002; 17.19.03.002; 18.04.04.004	0.001263%		Not Available
Cerebral venous thrombosis	17.08.03.002; 24.01.04.005	0.000842%		Not Available
Cerebrovascular accident	17.08.01.007; 24.03.05.001	-	-
Cheilitis	07.05.01.001; 23.03.03.025	0.003368%
Chest discomfort	02.02.02.009; 08.01.08.019; 22.02.08.001	-	-	Not Available
Chest pain	02.02.02.011; 08.01.08.002; 22.02.08.003	-	-	Not Available
Chills	08.01.09.001; 15.05.03.016	0.007156%
Choking	22.02.05.001	0.000842%		Not Available
Choking sensation	19.01.02.002; 22.02.05.002	0.000842%		Not Available

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