| Pharmaceutical Information |
| Drug Name |
Capromab pendetide |
| Drug ID |
BADD_D00352 |
| Description |
Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. When linked to pendetide, capromab is used as a chelating agent for the radionuclide [Indium In-111] during imaging to evaluate the extent of prostate cancer. |
| Indications and Usage |
For diagnosis of prostate cancer and detection of intra-pelvic metastases. |
| Marketing Status |
approved |
| ATC Code |
Not Available |
| DrugBank ID |
DB00089
|
| KEGG ID |
D03372
|
| MeSH ID |
C101315
|
| PubChem ID |
135509147
|
| TTD Drug ID |
D09PGL
|
| NDC Product Code |
Not Available |
| UNII |
BDO5072GRX
|
| Synonyms |
Capromab Pendetide | Indium-111-CYT-356 | (III)In-CYT-356 | Capromab | Cytogen 356 | CYT-356 | CYT 356 | Prostascint |
|
| Chemical Information |
| Molecular Formula |
C10H15N5O11P2 |
| CAS Registry Number |
145464-28-4 |
| SMILES |
C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)O)OP(=O)(O)O)O)N=C(NC2=O)N |
| Chemical Structure |
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| ADRs Induced by Drug |
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