Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Capreomycin
Drug ID BADD_D00350
Description Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.
Indications and Usage Used in the treatment of tuberculosis in combination with other drugs.
Marketing Status approved
ATC Code J04AB30
DrugBank ID DB00314
KEGG ID D07607
MeSH ID D002207
PubChem ID 3000502
TTD Drug ID D0E7MV
NDC Product Code Not Available
UNII 232HYX66HC
Synonyms Capreomycin | Capromycin | Capreomycin Sulfate | Capastat
Chemical Information
Molecular Formula C50H88N28O15
CAS Registry Number 11003-38-6
SMILES CC1C(=O)NC(C(=O)NC(=CNC(=O)N)C(=O)NC(C(=O)NCC(C(=O)N1)N)C2CCN=C(N2)N)CNC(=O)CC(C CCN)N.C1CN=C(NC1C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)NC(=CNC(=O)N)C(=O)N2)CNC(=O)CC(C CCN)N)CO)N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abscess sterile08.01.05.008---
Bromosulphthalein test abnormal13.03.04.021---
Deafness04.02.01.001---
Electrolyte imbalance14.05.01.002---
Eosinophilia01.02.04.001--
Injection site haemorrhage08.02.03.005; 12.07.03.005; 24.07.01.010---
Injection site induration08.02.03.007; 12.07.03.007---
Injection site pain08.02.03.010; 12.07.03.011---
Leukocytosis01.02.01.002--
Leukopenia01.02.02.001---
Nephropathy toxic12.03.01.010; 20.05.03.002---
Pyrexia08.05.02.003--
Rash maculo-papular23.03.13.004--
Thrombocytopenia01.08.01.002---
Tinnitus04.04.01.002; 17.04.07.004--
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
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