Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Candesartan
Drug ID BADD_D00346
Description Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of [candesartan cilexetil].
Indications and Usage Not Available
Marketing Status experimental
ATC Code C09CA06
DrugBank ID DB13919
KEGG ID D00522
MeSH ID C081643
PubChem ID 2541
TTD Drug ID D0D5SQ
NDC Product Code 68554-0038; 33342-114; 33342-117; 33342-116; 33342-115
UNII S8Q36MD2XX
Synonyms candesartan | 2-ethoxy-7-carboxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylbenzimidazole | 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-benzimidazole-7-carboxylic acid | CV 11974 | CV11974 | CV-11974
Chemical Information
Molecular Formula C24H20N6O3
CAS Registry Number 139481-59-7
SMILES CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gastroenteritis07.19.03.001; 11.01.07.004---
Gastrointestinal disorder07.11.01.001---
Gastrointestinal pain07.01.05.005--
Haematuria20.02.01.006; 21.10.01.018; 24.07.01.047--
Haemoglobin13.01.05.018---
Headache17.14.01.001--
Hepatitis09.01.07.004---
Hepatitis A09.01.09.004; 11.05.28.002---
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperkalaemia14.05.03.001--
Hypertension24.08.02.001--
Hypertriglyceridaemia14.08.02.001--
Hyperuricaemia14.09.01.003--
Hyponatraemia14.05.04.002--
Hypotension24.06.03.002--
Leukopenia01.02.02.001---
Myalgia15.05.02.001--
Myocardial infarction02.02.02.007; 24.04.04.009--
Nausea07.01.07.001--
Nephropathy20.05.03.001---
Neutropenia01.02.03.004---
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.011--
Palpitations02.11.04.012--
Paraesthesia17.02.06.005; 23.03.03.094--
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Pruritus23.03.12.001--
Rash23.03.13.001---
Renal failure20.01.03.005---
Rhabdomyolysis15.05.05.002--
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