| Pharmaceutical Information |
| Drug Name |
Calcitonin (salmon) |
| Drug ID |
BADD_D00336 |
| Description |
Synthetic peptide, 32 residues long formulated as a nasal spray. |
| Indications and Usage |
Used in the treatment of symptomatic Paget's disease for patients unresponsive to alternate treatments or intolerant to such treatments. In addition, it is used in emergency situations when serum calcium levels must be decreased quickly until the underlying condition is identified. It can also be added to existing therapeutic regimens for hypercalcemia such as intravenous fluids and furosemide, oral phosphate or corticosteroids, or other agents. Calcitonin can be used in patients with azotemia and cases where intravenous fluids would be contraindicated due to limited cardiac reserves. Also for the treatment of post-menopausal osteoporosis in women more than 5 years post-menopause. |
| Marketing Status |
approved; investigational |
| ATC Code |
Not Available |
| DrugBank ID |
DB00017
|
| KEGG ID |
D00249
|
| MeSH ID |
C028815
|
| PubChem ID |
16133812
|
| TTD Drug ID |
D0I1XG
|
| NDC Product Code |
35207-0003 |
| UNII |
7SFC6U2VI5
|
| Synonyms |
salmon calcitonin | synthetic salmon calcitonin | salmon calcitonin (1-32) | calcitonin salmon | salcatonin | Calcimar | Forcaltonin | recombinant salmon calcitonin | Miacalcic | Miacalcin | Calcihexal | Fortical |
|
| Chemical Information |
| Molecular Formula |
C145H240N44O48S2 |
| CAS Registry Number |
47931-85-1 |
| SMILES |
CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CC(=O)N)CO)N)C(=O)
NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C
CC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC2=CNC=N2)C(=O)NC(CCCCN)C(=O)NC
(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)N4CCCC4C(=O)
NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O
)NCC(=O)NC(C(C)O)C(=O)N5CCCC5C(=O)N)C(C)O)CO |
| Chemical Structure |
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| ADRs Induced by Drug |
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