| Drug Name |
Caffeine citrate |
| Drug ID |
BADD_D00333 |
| Description |
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to [Theophylline] and [Theobromine].[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, which are different than coffee beans.[T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally, by inhalation, or by injection.[T716]
The caffeine citrate injection, used for apnea of the premature newborn, was initially approved by the FDA in 1999.[L9863] According to an article from 2017, more than 15 million babies are born prematurely worldwide. This correlates to about 1 in 10 births. Premature birth can lead to apnea and bronchopulmonary dysplasia, a condition that interferes with lung development and may eventually cause asthma or early onset emphysema in those born prematurely.[A187694] Caffeine is beneficial in preventing and treating apnea and bronchopulmonary dysplasia in newborns, improving the quality of life of premature infants.[T716] |
| Indications and Usage |
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants. |
| Marketing Status |
Prescription |
| ATC Code |
D11AX26; N06BC01 |
| DrugBank ID |
DB00201
|
| KEGG ID |
D07603
|
| MeSH ID |
C026189
|
| PubChem ID |
6241
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
72485-110; 51754-0501; 63323-407; 42571-244; 51754-0500; 51754-0503; 0641-6164; 63323-406; 42571-346; 51754-0502; 0517-0020; 72485-104; 25021-602; 47335-290; 25021-601; 55150-187; 47335-289 |
| Synonyms |
caffeine citrate | Cafcit |
