Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Bumetanide
Drug ID BADD_D00307
Description Bumetanide is a sulfamyl diuretic.
Indications and Usage For the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.
Marketing Status approved
ATC Code C03CA02
DrugBank ID DB00887
KEGG ID D00247
MeSH ID D002034
PubChem ID 2471
TTD Drug ID D0R7HO
NDC Product Code 0832-0541; 60468-001; 72643-030; 0185-0129; 0641-6161; 0904-7016; 14501-0036; 17337-0055; 0185-0130; 50090-6137; 60687-535; 65219-570; 68382-526; 70518-3191; 71335-1692; 0641-6008; 17337-0011; 14539-702; 43353-288; 0185-0128; 50090-5666; 50090-6139; 50090-6345; 69238-1489; 70771-1025; 55154-4345; 65219-572; 68382-527; 69238-1491; 70518-2678; 72205-101; 0641-6162; 0832-0542; 55154-4733; 68462-469; 68462-470; 70860-405; 70860-406; 0615-8393; 0832-0540; 57755-0004; 63190-0370; 63190-0430; 42799-121; 50090-5068; 50090-5664; 70771-1026; 42799-120; 50090-5064; 50090-6138; 50268-132; 68083-497; 0409-1412; 14539-700; 50090-5663; 63629-4968; 68083-496; 72572-040; 72572-041; 60468-003; 42799-119; 50090-6308; 60687-384; 70771-1024; 72205-102; 0615-8394; 60468-002; 14539-701; 43353-292; 50090-6304; 50268-130; 50268-131; 55154-3572; 68382-525; 69238-1490; 0641-6007; 51662-1449
UNII 0Y2S3XUQ5H
Synonyms Bumetanide | Bumethanide | Bumex | PF-1593 | PF 1593 | PF1593 | Drenural | Fordiuran | Miccil | Bumedyl | Burinex
Chemical Information
Molecular Formula C17H20N2O5S
CAS Registry Number 28395-03-1
SMILES CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.0010.016328%
Nausea07.01.07.001--
Nipple pain21.05.05.009---
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.0110.000282%
Orthostatic hypotension17.05.01.020; 24.06.03.0040.000282%-
Pancreatitis07.18.01.001--
Polyuria20.02.03.0020.000706%-
Premature ejaculation19.08.01.002; 21.03.01.008---
Protein total abnormal13.09.01.008---
Prothrombin time13.01.02.038---
Pruritus23.03.12.0010.000763%
Rash23.03.13.0010.000763%-
Renal failure20.01.03.005---
Stevens-Johnson syndrome10.01.01.045; 11.07.01.005; 12.03.01.014; 23.03.01.007--
Syncope02.11.04.015; 17.02.04.008; 24.06.02.0120.000424%
Thrombocytopenia01.08.01.002---
Toxic epidermal necrolysis10.01.01.006; 11.07.01.006; 12.03.01.015; 23.03.01.008--
Urinary retention20.02.02.0110.000282%
Urticaria10.01.06.001; 23.04.02.0010.000763%
Vertigo04.04.01.003; 17.02.12.002--
Vomiting07.01.07.003--
White blood cell count13.01.06.027---
Hypoacusis04.02.01.006--
Peripheral swelling02.05.04.015; 08.01.03.0530.000621%-
Ear discomfort04.03.01.005---
Protein urine present13.13.02.006---
Blood phosphorus abnormal13.11.01.017---
Blood bilirubin abnormal13.03.04.016---
Blood alkaline phosphatase abnormal13.04.02.005---
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