Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Bumetanide
Drug ID BADD_D00307
Description Bumetanide is a sulfamyl diuretic.
Indications and Usage For the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.
Marketing Status Prescription; Discontinued
ATC Code C03CA02
DrugBank ID DB00887
KEGG ID D00247
MeSH ID D002034
PubChem ID 2471
TTD Drug ID D0R7HO
NDC Product Code 0185-0129; 17337-0011; 51662-1449; 50268-130; 30698-631; 50090-5123; 68071-4330; 60687-384; 50090-5663; 30698-630; 14539-701; 0641-6008; 69238-1489; 42799-120; 68071-3128; 68382-526; 50090-5064; 50268-131; 16714-832; 14539-700; 68382-527; 70518-2678; 14501-0036; 0904-7016; 60468-001; 72572-041; 0832-0542; 70860-405; 70771-1026; 0185-0130; 50090-5666; 43353-288; 0641-6007; 68382-525; 50268-132; 0409-1412; 14539-702; 50090-5124; 0832-0541; 42799-119; 0832-0540; 50090-5065; 57755-0004; 63629-7440; 55154-4733; 0615-8394; 70771-1024; 63190-0430; 16714-831; 0641-6161; 71335-1692; 60687-535; 71335-1201; 50090-5068; 63190-0370; 0615-8361; 0615-8362; 16714-833; 0615-8393; 63629-4968; 60468-003; 42799-121; 0185-0128; 43353-292; 72572-040; 70860-406; 69238-1491; 50090-5664; 55154-4345; 70771-1025; 71335-0016; 17337-0055; 68071-4350; 60468-002; 30698-632; 55154-3572; 70518-3191; 0641-6162; 69238-1490
Synonyms Bumetanide | Bumethanide | Bumex | PF-1593 | PF 1593 | PF1593 | Drenural | Fordiuran | Miccil | Bumedyl | Burinex
Chemical Information
Molecular Formula C17H20N2O5S
CAS Registry Number 28395-03-1
SMILES CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dyspnoea02.01.03.002; 22.02.01.0040.003861%
Electrocardiogram abnormal13.14.05.001--Not Available
Electrolyte imbalance14.05.01.002--Not Available
Encephalopathy17.13.02.001--
Erythema multiforme10.01.03.015; 23.03.01.003--
Fatigue08.01.01.002--
Fluid overload02.05.04.004; 14.05.06.0010.001931%Not Available
Fluid retention14.05.06.002; 20.01.02.0030.001931%Not Available
Gastrointestinal pain07.01.05.005--
Glycosuria20.02.01.005--
Glucose urine present13.13.02.001--Not Available
Gynaecomastia05.05.02.003; 21.05.04.003--
Haematocrit13.01.05.017--Not Available
Haemoglobin abnormal13.01.05.011--Not Available
Headache17.14.01.001--
Hepatocellular injury09.01.07.008--Not Available
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperkalaemia14.05.03.0010.001287%
Hyperuricaemia14.09.01.003--
Hyperventilation19.01.02.004; 22.02.01.006--Not Available
Hypochloraemia14.05.08.003--Not Available
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.0010.002574%
Hyponatraemia14.05.04.0020.004505%
Hypotension24.06.03.0020.003861%
Hypovolaemia14.05.05.0020.001287%Not Available
Leukopenia01.02.02.001--Not Available
Lip swelling07.05.04.005; 10.01.05.005; 23.04.01.0070.001287%Not Available
Malaise08.01.01.0030.001931%
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