Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Bromfenac
Drug ID BADD_D00300
Description Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool to optimize surgical outcomes.
Indications and Usage For the treatment of postoperative inflammation in patients who have undergone cataract extraction.
Marketing Status approved
ATC Code S01BC11
DrugBank ID DB00963
KEGG ID D07541
MeSH ID C053083
PubChem ID 60726
TTD Drug ID D0U1OM
NDC Product Code 65862-789; 49708-754; 68083-313; 50383-249; 72266-142
UNII 864P0921DW
Synonyms bromfenac | ISV-303 | Duract | sodium bromfenac | bromfenac sodium | Xibrom | AHR-10282
Chemical Information
Molecular Formula C15H12BrNO3
CAS Registry Number 91714-94-2
SMILES C1=CC(=C(C(=C1)C(=O)C2=CC=C(C=C2)Br)N)CC(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abnormal sensation in eye06.01.01.001---
Asthma10.01.03.010; 22.03.01.002---
Blepharitis06.04.04.001; 23.03.04.0120.001841%-
Burning sensation08.01.09.029; 17.02.06.0010.000921%-
Corneal epithelium defect06.06.03.0120.000271%-
Corneal erosion06.06.03.0030.000271%-
Corneal infiltrates06.08.01.002---
Corneal oedema06.04.02.001---
Corneal perforation06.06.03.006; 12.01.04.003---
Corneal scar06.06.03.015; 12.01.04.015---
Cough22.02.03.001--
Dermatitis allergic10.01.03.014; 23.03.04.0030.001841%-
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.0040.000921%-
Drug hypersensitivity10.01.01.0010.000596%-
Epistaxis22.04.03.001; 24.07.01.005--
Eye discharge06.04.05.001---
Eye disorder06.08.03.001---
Eye irritation06.04.05.0030.004603%-
Eye pain06.08.03.0020.000921%
Eye swelling06.08.03.0030.000921%-
Headache17.14.01.001--
Iritis06.04.03.002; 10.02.01.022---
Keratitis06.04.02.0020.000271%
Mydriasis06.05.03.004; 17.02.11.0030.000271%-
Ocular hyperaemia06.04.05.0040.000921%-
Pain08.01.08.004--
Photophobia06.01.01.004; 17.17.02.006--
Punctate keratitis06.04.02.0030.000271%-
Retinal disorder06.08.03.005---
Retinal exudates05.07.01.007; 06.10.02.003; 14.07.01.007; 24.03.07.007---
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