Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bromazepam
Drug ID BADD_D00299
Description One of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Indications and Usage For the short-term treatment of insomnia, short-term treatment of anxiety or panic attacks, if a benzodiazepine is required, and the alleviation of the symptoms of alcohol- and opiate-withdrawal.
Marketing Status approved; illicit; investigational
ATC Code N05BA08
DrugBank ID DB01558
KEGG ID D01245
MeSH ID D001960
PubChem ID 2441
TTD Drug ID D0E3FD
NDC Product Code Not Available
UNII X015L14V0O
Synonyms Bromazepam | Apo-Bromazepam | Apo Bromazepam | BromaLich | Bromaz 1A Pharma | Bromazanil | Bromazep Von Ct | Von Ct, Bromazep | Bromazepam AL | Bromazepam Beta | Beta, Bromazepam | Bromazepam Heumann | Bromazepam-Neuraxpharm | Bromazepam Neuraxpharm | Bromazepam-Ratiopharm | Bromazepam Ratiopharm | Durazanil | Gen-Bromazepam | Gen Bromazepam | Lexotan | Lexomil | Lexatin | Lexotanil | Ro 5-3350 | Ro 53350 | Anxyrex
Chemical Information
Molecular Formula C14H10BrN3O
CAS Registry Number 1812-30-2
SMILES C1C(=O)NC2=C(C=C(C=C2)Br)C(=N1)C3=CC=CC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypotension24.06.03.002--
Incontinence07.01.06.011; 17.05.01.006; 20.02.02.004---
Irritability08.01.03.011; 19.04.02.013--
Multiple fractures12.04.02.009; 15.08.02.005---
Muscle spasms15.05.03.004--
Muscular weakness15.05.06.001; 17.05.03.005--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001---
Nervousness19.06.02.003---
Nightmare19.02.03.003---
Palpitations02.11.04.012--
Pruritus23.03.12.001--
Rash23.03.13.001---
Respiratory depression17.02.05.047; 22.02.01.010---
Seizure17.12.03.001--
Skin disorder23.03.03.007---
Sleep disorder19.02.04.001---
Somnolence17.02.04.006; 19.02.05.003--
Speech disorder17.02.08.003; 19.19.02.002; 22.12.03.027---
Tachycardia02.03.02.007---
Tension19.06.02.005---
Tremor17.01.06.002--
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
White blood cell count decreased13.01.06.012--
Cardiac disorder02.11.01.003---
Connective tissue disorder10.04.04.026; 15.06.01.006---
Malnutrition14.03.02.004---
Mental disorder19.07.01.002---
Decreased appetite08.01.09.028; 14.03.01.005--
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