| Pharmaceutical Information |
| Drug Name |
Bisoprolol |
| Drug ID |
BADD_D00277 |
| Description |
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs.[A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and [Labetalol]. It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity.[A180562] |
| Indications and Usage |
Bisoprolol is indicated for the treatment of mild to moderate hypertension.[L7219] It may be used off-label to treat heart failure, atrial fibrillation, and angina pectoris.[A180460,A180463] |
| Marketing Status |
approved |
| ATC Code |
C07AB07 |
| DrugBank ID |
DB00612
|
| KEGG ID |
D02342
|
| MeSH ID |
D017298
|
| PubChem ID |
2405
|
| TTD Drug ID |
D0K3ZR
|
| NDC Product Code |
Not Available |
| UNII |
Y41JS2NL6U
|
| Synonyms |
Bisoprolol | Bisoprolol Fumarate (1:1) Salt, (+-)-Isomer | Bisoprolol Fumarate (2:1) Salt, (+-)-Isomer | Bisoprolol Hydrochloride | Hydrochloride, Bisoprolol | Bisoprolol Methanesulfonate Salt | Bisoprolol, (+-)-Isomer | Bisoprolol, Fumarate (1:1) Salt | Bisoprolol, Fumarate (2:1) Salt | CL-297939 | CL 297939 | CL297939 | Concor | EMD-33512 | EMD 33512 | EMD33512 | Bisoprolol Fumarate | Fumarate, Bisoprolol | Bisoprolol, (-)-Isomer |
|
| Chemical Information |
| Molecular Formula |
C18H31NO4 |
| CAS Registry Number |
66722-44-9 |
| SMILES |
CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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