Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bisacodyl
Drug ID BADD_D00276
Description Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]
Indications and Usage Bisacodyl is indicated to relieve occasional constipation and irregularity.[L13362]
Marketing Status approved
ATC Code A06AB02; A06AG02
DrugBank ID DB09020
KEGG ID D00245
MeSH ID D001726
PubChem ID 2391
TTD Drug ID D07IEF
NDC Product Code 80136-871; 61876-0002; 30142-827; 41167-0290; 41415-121; 55315-190; 63941-120; 63941-190; 68016-688; 68210-3120; 68210-4106; 71335-2010; 12828-0015; 38779-3146; 51927-0115; 21130-676; 24689-129; 36800-190; 37808-676; 41163-195; 41167-0200; 41167-0400; 41250-191; 50804-327; 62011-0403; 67091-215; 68163-116; 58793-002; 10237-906; 11822-0327; 36800-676; 41520-019; 49035-327; 53943-805; 55319-327; 55910-120; 57896-443; 59779-706; 63940-327; 69846-140; 70795-1010; 72476-845; 72476-960; 55910-457; 56062-676; 57896-441; 67091-385; 70000-0538; 71610-453; 71890-330; 16990-010; 68210-1022; 21130-827; 36800-327; 41163-607; 50844-697; 59779-676; 0363-0327; 69842-816; 70000-0570; 70000-0573; 70518-2976; 0904-6748; 11822-0676; 11822-7850; 24385-903; 41167-0101; 41226-003; 41226-151; 41250-339; 41415-116; 49483-003; 55910-850; 57648-002; 70677-1091; 11673-151; 41250-676; 43749-460; 46122-529; 49348-032; 53943-676; 59726-190; 63868-573; 67091-286; 68016-197; 68784-102; 69618-058; 69842-089; 70518-1864; 0574-7050; 71335-1531; 71399-8460; 79903-178; 12579-228; 69617-008; 83221-001; 37808-327; 55301-676; 55910-327; 58980-415; 59779-327; 62011-0277; 0363-3011; 0363-6760; 63868-209; 68016-084; 68998-398; 70000-0221; 70000-0228; 70677-1086; 76457-003; 62485-036; 11673-116; 21130-410; 41167-0210; 41250-665; 49035-706; 50844-327; 55319-195; 56062-327; 63868-328; 63868-908; 71335-1750; 72476-654; 0904-6407; 49706-0650; 30142-191; 37808-877; 46122-429; 50804-190; 55319-607; 55910-168; 55910-190; 55910-253; 63868-572; 71335-1754; 71610-700; 72701-102; 81440-102; 12579-230; 0904-7142; 11822-0790; 33992-0327; 0132-0703; 46122-608; 50804-120; 55154-6897; 55910-954
UNII 10X0709Y6I
Synonyms Bisacodyl | Durolax | Apo-Bisacodyl | Apo Bisacodyl | Bekunis Bisacodyl | Bisacodyl, Bekunis | Bicol | Bisac-Evac | Bisac Evac | Bisacodyl Tannex | Tannex, Bisacodyl | Bisacodyl Uniserts | Uniserts, Bisacodyl | Ulcolax | Bisalax | Bisco-Lax | Bisco Lax | Lünolax | Bisco-Zitron | Bisco Zitron | Dulcolax | Dulco-Lax | Dulco Lax | Fleet Bisacodyl | Bisacodyl, Fleet | Laxagetten | Laxanin | Laxans-ratiopharm | Laxans ratiopharm | Laxbene | Laxysat Bürger | Florisan N | ratio-Bisacodyl | ratio Bisacodyl | Dulco-lax perles | Dulco lax perles | Dulcolax perles | Rytmil | Agaroletten
Chemical Information
Molecular Formula C22H19NO4
CAS Registry Number 603-50-9
SMILES CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Abdominal rigidity07.01.05.011---
Ageusia07.14.03.003; 17.02.07.001---
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Asthenia08.01.01.001---
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.002---
Chills08.01.09.001; 15.05.03.016--
Cold sweat08.01.03.024; 23.02.03.002---
Colitis07.08.01.001--
Colitis ischaemic07.08.01.004; 24.04.08.012---
Constipation07.02.02.001--
Dehydration14.05.05.001--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Drug abuse19.07.06.010---
Drug dependence19.07.06.011---
Drug ineffective08.06.01.006---
Dry mouth07.06.01.002--
Feeling abnormal08.01.09.014---
Feeling hot08.01.09.009---
Flatulence07.01.04.002--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
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ADReCS-Target
Drug Name ADR Term Target
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