Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Benzphetamine hydrochloride
Drug ID BADD_D00243
Description A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Indications and Usage For the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction
Marketing Status approved; illicit
ATC Code Not Available
DrugBank ID DB00865
KEGG ID D07515
MeSH ID D001589
PubChem ID 11558159
TTD Drug ID D0T5UL
NDC Product Code 0406-9223; 14593-837; 71335-0451; 17337-0010; 50090-5837; 61960-7600; 17224-672; 42806-081; 43063-541; 10702-040; 50090-1024
UNII 43DWT87QT7
Synonyms Benzphetamine | Benzfetamine | Didrex
Chemical Information
Molecular Formula C17H22ClN
CAS Registry Number 5411-22-3
SMILES CC(CC1=CC=CC=C1)N(C)CC2=CC=CC=C2.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood pressure increased13.14.03.005---
Cardiomyopathy02.04.01.001---
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Gastrointestinal disorder07.11.01.001---
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Insomnia17.15.03.002; 19.02.01.002--
Myocardial ischaemia02.02.02.008; 24.04.04.010---
Nausea07.01.07.001--
Palpitations02.11.04.012--
Restlessness17.02.05.021; 19.11.02.002--
Tachycardia02.03.02.007---
Tremor17.01.06.002--
Urticaria10.01.06.001; 23.04.02.001--
Libido disorder19.08.03.004; 21.03.02.006---
Cardiac valve disease02.07.02.001---
Psychotic disorder19.03.01.002--
Device stimulation issue27.01.02.005---
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