| Pharmaceutical Information |
| Drug Name |
Benzocaine hydrochloride |
| Drug ID |
BADD_D00238 |
| Description |
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.[A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259] |
| Indications and Usage |
Benzocaine is indicated for local anesthesia in dentistry, minor trauma, and as preparation for infiltrative anesthesia.[A231219] Benzocaine products are indicated for topical anesthesia in a wide variety of conditions including skin irritation,[L32454] oral pain,[L32459] and hemorrhoids.[L32464] |
| Marketing Status |
approved; investigational |
| ATC Code |
D04AB04; R02AD01; N01BA05; C05AD03 |
| DrugBank ID |
DB01086
|
| KEGG ID |
D00552
|
| MeSH ID |
D001566
|
| PubChem ID |
10214462
|
| TTD Drug ID |
D0Q8ZX
|
| NDC Product Code |
57554-120 |
| UNII |
OG625Z9LEO
|
| Synonyms |
Benzocaine | 4-Aminobenzoic Acid Ethyl Ester | Bensokain | Ethyl Aminobenzoate | Anaesthesin | Anesthesin | Benzocaine Hydrobromide | Hydrobromide, Benzocaine | Benzocaine Hydrochloride | Hydrochloride, Benzocaine | Benzocaine Acetate | Acetate, Benzocaine | Benzocaine Methanesulfonate | Methanesulfonate, Benzocaine | Ethoform | Americaine | Benzocaine Formate | Formate, Benzocaine |
|
| Chemical Information |
| Molecular Formula |
C9H12ClNO2 |
| CAS Registry Number |
23239-88-5 |
| SMILES |
CCOC(=O)C1=CC=C(C=C1)N.Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Rash | 23.03.13.001 | - | - | - | | Skin irritation | 23.03.04.009 | - | - | - |
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