Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Barium sulfate
Drug ID BADD_D00213
Description Barium sulfate is an inorganic compound with the chemical formula BaSO4 [L1957]. Barium sulfate occurs in nature as the mineral _barite_. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield [L1957]. This drug is used as a contrast agent in diagnostic x-ray procedures. Therapeutic advantages of barium sulfate in diagnostic procedures include both its low water solubility and high level of clearance from the body [FDA label]. Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent bicarbonate to enhance distension of the GI tract, allowing for enhanced gastrointestinal tract visualization [L1957], [L1959].
Indications and Usage Barium sulfate is a radiographic contrast agent indicated for use in computed tomography (CT) of the abdomen to delineate the gastrointestinal (GI) tract in adult and pediatric patients [FDA label].
Marketing Status Prescription; Discontinued
ATC Code Not Available
DrugBank ID DB11150
KEGG ID D02052
MeSH ID D001466
PubChem ID 24414
TTD Drug ID D0T5DE
NDC Product Code 32909-125; 32909-116; 32909-722; 32909-756; 32909-770; 32909-814; 32909-746; 32909-105; 32909-724; 69307-1024; 32909-741; 32909-744; 32909-187; 32909-742; 10361-778; 32909-747; 32909-927; 32909-115; 0395-0200; 32909-122; 32909-167; 32909-146; 32909-764; 32909-121; 75855-3470; 32909-750; 32909-711; 75855-3471
Synonyms Barium Sulfate | Sulfate, Barium | Micropaque Oral | Barium Sulfate (2:1) | E-Z-CAT | E Z CAT | EZCAT | Barite | Baritop
Chemical Information
Molecular Formula BaSO4
CAS Registry Number 7727-43-7
SMILES [O-]S(=O)(=O)[O-].[Ba+2]
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation17.02.05.012; 19.06.02.001--
Asthenia08.01.01.001--Not Available
Bacteraemia11.01.11.001--
Bradycardia02.03.02.002--Not Available
Bronchospasm10.01.03.012; 22.03.01.004--
Confusional state17.02.03.005; 19.13.01.001--
Cyanosis02.01.02.002; 22.02.02.007; 24.03.01.007--
Death08.04.01.001--
Diarrhoea07.02.01.001--
Dyspnoea02.01.03.002; 22.02.01.004--
Erythema23.03.06.001--Not Available
Granuloma08.01.05.001; 23.03.15.001--Not Available
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypotension24.06.03.002--
Intestinal perforation07.04.06.002--Not Available
Laryngeal oedema10.01.05.003; 22.04.02.001; 23.04.01.005--
Loss of consciousness17.02.04.004--Not Available
Nausea07.01.07.001--
Pallor08.01.03.032; 23.03.03.031; 24.03.04.001--Not Available
Peritonitis07.19.05.004; 11.01.07.007--
Pneumonia aspiration22.01.01.005--Not Available
Pneumonitis22.01.01.006--
Pruritus23.03.12.001--
Sepsis11.01.11.003--
Syncope02.01.02.008; 17.02.04.008; 24.06.02.012--
Tachycardia02.03.02.007--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Urticaria10.01.06.001; 23.04.02.001--
Vasodilatation23.06.05.006; 24.03.02.003--Not Available
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