| Pharmaceutical Information |
| Drug Name |
Balsalazide disodium |
| Drug ID |
BADD_D00211 |
| Description |
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt.
Balsalazide works by deliverying mesalazine to the large intestine to act directly on ulcerative colitis. Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA. |
| Indications and Usage |
For the treatment of mildly to moderately active ulcerative colitis. |
| Marketing Status |
approved; investigational |
| ATC Code |
A07EC04 |
| DrugBank ID |
DB01014
|
| KEGG ID |
D02715
|
| MeSH ID |
C038637
|
| PubChem ID |
135413496
|
| TTD Drug ID |
D0A6KR
|
| NDC Product Code |
60505-2575; 12598-7129; 72789-149; 50268-102; 0054-0079; 68682-750; 65649-101; 12598-6026 |
| UNII |
1XL6BJI034
|
| Synonyms |
balsalazide | 5-(carboxyethylcarbamoyl-4-phenylazo)salicylic acid | BX 661A | BX661A | Colazide | balsalazine | balsalazide disodium | Colazal |
|
| Chemical Information |
| Molecular Formula |
C17H13N3Na2O6 |
| CAS Registry Number |
82101-18-6 |
| SMILES |
C1=CC(=CC=C1C(=O)NCCC(=O)[O-])N=NC2=CC(=C(C=C2)[O-])C(=O)O.[Na+].[Na+] |
| Chemical Structure |
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| ADRs Induced by Drug |
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