Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Atropine sulfate
Drug ID BADD_D00190
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status Prescription; Discontinued
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D02069
MeSH ID D001285
PubChem ID 60196398
TTD Drug ID D0RG3O
NDC Product Code 51662-1509; 51662-1527; 0404-9823; 0404-9822; 13985-606; 52584-630; 0409-1630; 51552-1391; 0641-6006; 50268-118; 71872-7100; 70518-3120; 38779-2267; 71872-7037; 52584-002; 76329-3340; 51662-1339; 50090-4524; 51662-1311; 0404-9820; 52584-401; 63323-580; 50090-5924; 16729-512; 0409-4910; 50090-3138; 0409-4911; 16729-483; 52584-910; 0404-9821; 71872-7255; 0404-9824; 52584-029; 13371-387; 63827-1014; 71872-7002; 69205-736; 71872-7001; 71872-7245; 0517-1010; 0641-6251; 0404-9819; 16729-484; 76329-3339; 0409-9630; 16729-526; 43235-0004; 51662-1378; 51662-1289; 50090-3104; 52584-044; 51662-1207; 12714-031; 42385-736; 17478-215; 71684-0303; 70121-1705; 0517-0401; 62991-2842; 60505-6226; 62068-306; 52221-107; 55742-124; 76003-0157; 51662-1208; 71872-7246; 69205-031; 16729-525; 71872-7017; 0065-0303; 71872-7252; 24208-825; 51927-0156
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augen？l | Augen？l, Atropin
Chemical Information
Molecular Formula C34H48N2O10S
CAS Registry Number 55-48-1
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.OS(= O)(=O)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Generalised tonic-clonic seizure17.12.01.002--Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemoglobin increased13.01.05.004--
Hallucination19.10.02.002--
Hallucination, auditory19.10.02.003--Not Available
Hallucination, visual19.10.02.004--Not Available
Headache17.14.01.001--
Heterophoria06.05.02.001; 17.02.05.017--Not Available
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperpyrexia08.05.02.002--Not Available
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Hypertonia15.05.04.007; 17.05.02.001--Not Available
Hypoaesthesia eye06.01.01.007; 17.02.06.019--Not Available
Hypoglycaemia05.06.03.001; 14.06.03.001--
Hypokalaemia14.05.03.002--
Hyponatraemia14.05.04.002--
Ileus paralytic07.02.05.001--Not Available
Impaired gastric emptying07.02.02.004--
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia17.15.03.002; 19.02.01.002--
Irritability08.01.03.011; 19.04.02.013--
Labile blood pressure24.06.01.001--Not Available
Lacrimation increased06.08.02.004--
Laryngitis11.01.13.001; 22.07.03.001--
Laryngospasm22.04.02.002--
Left ventricular failure02.05.02.001--Not Available
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004--
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