Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Atropine sulfate
Drug ID BADD_D00190
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status approved; vet_approved
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D02069
MeSH ID D001285
PubChem ID 60196398
TTD Drug ID D0RG3O
NDC Product Code 69205-031; 51662-1527; 0409-4910; 71872-7037; 0065-0303; 76329-3340; 50090-3104; 50268-118; 51662-1339; 60219-1749; 0404-9822; 71872-7246; 16729-483; 16729-525; 17478-215; 51662-1289; 51662-1378; 60505-6226; 63323-580; 0404-9820; 0517-1004; 70121-1705; 71872-7001; 60219-1750; 0517-1001; 62068-306; 62991-2842; 71684-0303; 76003-0157; 16729-484; 51662-1619; 51662-1626; 0409-1630; 0409-4911; 0409-9630; 0517-1010; 71872-7245; 71872-7252; 0065-0817; 82260-001; 12714-031; 51662-1311; 51662-1627; 0404-9821; 71872-7002; 0641-6006; 76478-015; 69205-736; 16729-526; 24208-825; 51662-1509; 42385-736; 43235-0004; 16729-512; 24208-965; 50090-5924; 51662-1208; 52584-002; 52584-910; 71872-7298; 0641-6251; 38779-2267; 55742-124; 63827-1014; 52584-630; 0517-0401; 71872-7100; 13371-387; 51552-1391; 52221-107; 13985-606; 50090-6295; 51662-1207; 60219-1748
UNII 03J5ZE7KA5
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augenöl | Augenöl, Atropin
Chemical Information
Molecular Formula C34H48N2O10S
CAS Registry Number 55-48-1
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.OS(= O)(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Generalised tonic-clonic seizure17.12.01.002---
Haemoglobin decreased13.01.05.003---
Haemoglobin increased13.01.05.004--
Hallucination19.10.04.003--
Hallucination, auditory19.10.04.004---
Hallucination, visual19.10.04.007---
Headache17.14.01.001--
Heterophoria06.05.02.001; 17.02.05.017---
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperpyrexia08.05.02.002---
Hyperreflexia17.02.01.002---
Hypersensitivity10.01.03.003--
Hypertonia15.05.04.007; 17.05.02.001---
Hypoaesthesia eye06.01.01.007; 17.02.06.019---
Hypoglycaemia05.06.03.001; 14.06.03.001--
Hypokalaemia14.05.03.002--
Hyponatraemia14.05.04.002--
Ileus paralytic07.02.05.001---
Impaired gastric emptying07.02.02.004--
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia17.15.03.002; 19.02.01.002--
Irritability08.01.03.011; 19.04.02.013--
Labile blood pressure24.06.01.001---
Lacrimation increased06.08.02.004--
Laryngitis11.01.13.001; 22.07.03.001--
Laryngospasm22.04.02.002--
Left ventricular failure02.05.02.001---
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004--
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