Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Atropine
Drug ID BADD_D00189
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status Prescription; Discontinued
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D00113
MeSH ID D001285
PubChem ID 174174
TTD Drug ID D0RG3O
NDC Product Code 69205-034; 60592-049; 11704-105; 63827-1015; 13371-488; 12714-034; 11704-106; 64181-0048; 11704-107; 11704-101; 11704-104
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augen？l | Augen？l, Atropin
Chemical Information
Molecular Formula C17H23NO3
CAS Registry Number 51-55-8
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyponatraemia14.05.04.002--
Hypotension24.06.03.0020.001030%
Hypotonia15.05.04.008; 17.05.02.0020.000687%Not Available
Ileus paralytic07.02.05.001--Not Available
Impaired gastric emptying07.02.02.004--
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia17.15.03.002; 19.02.01.002--
Intraocular pressure increased13.07.04.0020.000687%Not Available
Irritability08.01.03.011; 19.04.02.013--
Keratitis06.04.02.002--
Labile blood pressure24.06.01.001--Not Available
Lacrimation decreased06.08.02.007--Not Available
Laryngitis11.01.13.001; 22.07.03.001--
Laryngospasm22.04.02.002--
Left ventricular failure02.05.02.001--Not Available
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004--
Leukocytosis01.02.01.002--
Loss of consciousness17.02.04.004--Not Available
Loss of libido19.08.03.003--Not Available
Mania19.16.02.002--
Miosis06.05.03.003; 17.02.11.0020.000687%Not Available
Mucosal dryness08.01.06.0010.000687%Not Available
Muscle twitching15.05.03.005--Not Available
Mydriasis06.05.03.004; 17.02.11.0030.003777%Not Available
Myocardial infarction02.02.02.007; 24.04.04.009--
Myopia06.02.04.002--Not Available
Nasal congestion22.04.04.001--
Nasal dryness22.04.03.002--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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