Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Articaine hydrochloride
Drug ID BADD_D00170
Description Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Indications and Usage Not Available
Marketing Status approved
ATC Code N01BB08
DrugBank ID DB09009
KEGG ID D02991
MeSH ID D002355
PubChem ID 32169
TTD Drug ID D0I5HV
NDC Product Code 53335-0001; 65675-1004; 68108-0610
UNII QS9014Q792
Synonyms Carticaine | Carticain | Articain | Articaine | Carticaine Hydrochloride | Hydrochloride, Carticaine | Hoe-40045 | Hoe 40045 | Hoe40045 | Hoe-045 | Hoe 045 | Hoe045 | Ultracaine
Chemical Information
Molecular Formula C13H21ClN2O3S
CAS Registry Number 161448-79-9
SMILES CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tachycardia02.03.02.007---
Tension19.06.02.005---
Thirst08.01.09.021; 14.03.02.007---
Tooth disorder07.09.05.001---
Trismus15.05.04.004; 17.01.03.004--
Vomiting07.01.07.003--
Kearns-Sayre syndrome02.04.01.006; 03.18.01.001; 06.05.02.016; 15.05.05.009; 17.17.01.019---
Musculoskeletal discomfort15.03.04.001---
Haemorrhage24.07.01.002---
Paraesthesia oral07.05.05.035; 17.02.06.008---
Ill-defined disorder08.01.03.049---
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