Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Arformoterol
Drug ID BADD_D00159
Description Arformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing. Arformoterol inhalation is used to prevent bronchoconstriction in people with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. The use of arformoterol is pending revision due to safety concerns in regards to an increased risk of severe exacerbation of asthma symptoms, leading to hospitalization as well as death in some patients using long acting beta agonists for the treatment of asthma.
Indications and Usage A bronchodilator used for the long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Marketing Status Prescription; Discontinued
ATC Code R03AC13; R03CC15
DrugBank ID DB01274
KEGG ID D01373
MeSH ID D000068759
PubChem ID 3083544
TTD Drug ID D0D1DI
NDC Product Code Not Available
Synonyms Formoterol Fumarate | Formoterol Fumarate, ((R*,R*)-(+-))-isomer | 3-Formylamino-4-hydroxy-alpha-(N-1-methyl-2-p-methoxyphenethylaminomethyl)benzyl alcohol.hemifumarate | BD 40A | Formoterol | Eformoterol | Oxis | Arformoterol | Formoterol, ((R*,R*)-(+-))-isomer | Foradil
Chemical Information
Molecular Formula C19H24N2O4
CAS Registry Number 67346-49-0
SMILES CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Electrocardiogram QT prolonged13.14.05.004--
Electrocardiogram T wave inversion13.14.05.007--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastritis07.08.02.001--
Glaucoma06.03.01.002--
Glucose tolerance decreased13.02.02.004--Not Available
Glycosuria20.02.01.005--
Gout14.09.01.001; 15.01.06.001--Not Available
Haematuria20.02.01.006; 24.07.01.047--
Headache17.14.01.001--
Hernia08.01.04.001--Not Available
Herpes simplex11.05.02.001; 23.09.03.001--Not Available
Herpes zoster11.05.02.003; 23.09.03.002--
Hypercalciuria05.04.01.003; 14.04.01.006; 20.02.01.007--Not Available
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoglycaemia05.06.03.001; 14.06.03.001--
Hypokalaemia14.05.03.002--
Hypokinesia17.01.02.009--Not Available
Hypotension24.06.03.002--
Influenza11.05.03.001; 22.07.02.001--Not Available
Injection site pain08.02.03.010; 12.07.03.011--Not Available
Insomnia17.15.03.002; 19.02.01.002--
Leukocytosis01.02.01.002--
Lung disorder22.02.07.001--Not Available
Malaise08.01.01.003--
Melaena07.12.02.004; 24.07.02.013--Not Available
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