| Pharmaceutical Information |
| Drug Name |
Apraclonidine |
| Drug ID |
BADD_D00154 |
| Description |
Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist. |
| Indications and Usage |
For prevention or reduction of intraoperative and postoperative increases in intraocular pressure (IOP) before and after ocular laser surgery when used prophylactically. Also used as a short-term adjunctive therapy in patients with open-angle glaucoma who are on maximally tolerated medical therapy requiring additional IOP reduction. |
| Marketing Status |
approved |
| ATC Code |
S01EA03 |
| DrugBank ID |
DB00964
|
| KEGG ID |
D07461
|
| MeSH ID |
C016986
|
| PubChem ID |
2216
|
| TTD Drug ID |
D0MT0M
|
| NDC Product Code |
61314-665 |
| UNII |
843CEN85DI
|
| Synonyms |
apraclonidine | 4-aminoclonidine | para-aminoclonidine | 2-(4-amino-2,6-dichloro)phenyliminoimidazolidine | p-aminoclonidine | apraclonidine hydrochloride | Iopidine | Iopimax | ALO 2145 | ALO-2145 |
|
| Chemical Information |
| Molecular Formula |
C9H10Cl2N4 |
| CAS Registry Number |
66711-21-5 |
| SMILES |
C1CN=C(N1)NC2=C(C=C(C=C2Cl)N)Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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