Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ampicillin trihydrate
Drug ID BADD_D00135
Description Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Indications and Usage For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc
Marketing Status approved; vet_approved
ATC Code S01AA19; J01CA01
DrugBank ID DB00415
KEGG ID D01251
MeSH ID D000667
PubChem ID 23565
TTD Drug ID D0YA9Z
NDC Product Code 66558-0060; 59651-771; 65862-275; 65862-461
UNII HXQ6A1N7R6
Synonyms Ampicillin | Aminobenzylpenicillin | Penicillin, Aminobenzyl | Aminobenzyl Penicillin | Ampicillin Sodium | Sodium, Ampicillin | Ampicillin Trihydrate | Trihydrate, Ampicillin | Antibiotic KS-R1 | Antibiotic KS R1 | KS-R1, Antibiotic | Pentrexyl | Polycillin | Ukapen | Amcill | Omnipen
Chemical Information
Molecular Formula C16H19N3O4S.3H2O
CAS Registry Number 7177-48-2
SMILES CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.O.O.O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001---
Anaemia01.03.02.001--
Congenital laryngeal stridor03.16.02.001; 22.10.02.001---
Dermatitis exfoliative10.01.01.004; 23.03.07.001--
Diarrhoea07.02.01.001--
Enterocolitis07.08.03.003--
Eosinophilia01.02.04.001--
Erythema multiforme10.01.03.015; 23.03.01.003--
Glossitis07.14.01.001---
Hyperpyrexia08.05.02.002---
Leukopenia01.02.02.001---
Nausea07.01.07.001--
Pruritus23.03.12.001--
Pseudomembranous colitis07.19.01.003; 11.02.02.002---
Rash23.03.13.001---
Rash erythematous23.03.13.029---
Rash maculo-papular23.03.13.004--
Rash pruritic23.03.13.030---
Stomatitis07.05.06.005--
Thrombocytopenia01.08.01.002---
Thrombocytopenic purpura01.08.01.003; 23.06.01.007---
Urticaria10.01.06.001; 23.04.02.001--
Vomiting07.01.07.003--
Transaminases increased13.03.04.036---
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