| Drug Name |
Amphotericin b |
| Drug ID |
BADD_D00132 |
| Description |
Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses. |
| Indications and Usage |
Used to treat potentially life threatening fungal infections. |
| Marketing Status |
approved; investigational |
| ATC Code |
A01AB04; A07AA07; G01AA03; J02AA01 |
| DrugBank ID |
DB00681
|
| KEGG ID |
D00203
|
| MeSH ID |
D000666
|
| PubChem ID |
14956
|
| TTD Drug ID |
D02DWM
|
| NDC Product Code |
65044-7183; 62756-233; 38779-0191; 51552-0304; 51927-1726; 62991-1173; 39822-1055; 55500-0001; 63622-0123; 63622-0124; 63622-0125; 0469-3051; 39635-0003; 45932-0008; 55150-365 |
| UNII |
7XU7A7DROE
|
| Synonyms |
Amphotericin B | Amphotericin | Fungizone | Amphotericin B Cholesterol Dispersion | Amphotericin B Colloidal Dispersion | Amphocil |
