| Pharmaceutical Information |
| Drug Name |
Ammonium chloride |
| Drug ID |
BADD_D00124 |
| Description |
Ammonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions. |
| Indications and Usage |
1. Expectorant in cough syrups.
2. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium (Na+) to combine with fixed anions in maintaining acid-base balance, especially as a homeostatic compensatory mechanism in metabolic acidosis.
The therapeutic effects of Ammonium Chloride depend upon the ability of the kidney to utilize ammonia in the excretion of an excess of fixed anions and the conversion of ammonia to urea by the liver, thereby liberating hydrogen (H+) and chloride (Cl–) ions into the extracellular fluid.
Ammonium Chloride Injection, USP, after dilution in isotonic sodium chloride injection, may be indicated in the treatment of patients with:
(1) hypochloremic states and (2) metabolic alkalosis. |
| Marketing Status |
approved; investigational; vet_approved |
| ATC Code |
B05XA04; G04BA01 |
| DrugBank ID |
DB06767
|
| KEGG ID |
D01139
|
| MeSH ID |
D000643
|
| PubChem ID |
25517
|
| TTD Drug ID |
D06WEK
|
| NDC Product Code |
64117-204; 0220-0249; 57467-267; 62106-4838; 49452-0520 |
| UNII |
01Q9PC255D
|
| Synonyms |
Ammonium Chloride | Chloride, Ammonium | Sal Ammoniac | Ammoniac, Sal |
|
| Chemical Information |
| Molecular Formula |
ClH4N |
| CAS Registry Number |
12125-02-9 |
| SMILES |
[NH4+].[Cl-] |
| Chemical Structure |
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| ADRs Induced by Drug |
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