Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Aminohippuric acid
Drug ID BADD_D00109
Description The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Indications and Usage Used to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.
Marketing Status approved; investigational
ATC Code V04CH30
DrugBank ID DB00345
KEGG ID D06890
MeSH ID D010130
PubChem ID 2148
TTD Drug ID D04DLM
NDC Product Code Not Available
UNII Y79XT83BJ9
Synonyms p-Aminohippuric Acid | p Aminohippuric Acid | para-Aminohippuric Acid | para Aminohippuric Acid | 4-Aminohippuric Acid | 4 Aminohippuric Acid | Aminohippuric Acid | Nephrotest | p-Aminohippurate | p Aminohippurate | Aminohippurate Sodium | Sodium, Aminohippurate | Sodium Para-Aminohippurate | Para-Aminohippurate, Sodium | Sodium Para Aminohippurate
Chemical Information
Molecular Formula C9H10N2O3
CAS Registry Number 61-78-9
SMILES C1=CC(=CC=C1C(=O)NCC(=O)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic shock10.01.07.002; 24.06.02.004---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Feeling hot08.01.09.009---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Hypersensitivity10.01.03.003--
Muscle spasms15.05.03.004--
Nausea07.01.07.001--
Paraesthesia17.02.06.005; 23.03.03.094--
Urticaria10.01.06.001; 23.04.02.001--
Vomiting07.01.07.003--
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