| Pharmaceutical Information |
| Drug Name |
Adenosine |
| Drug ID |
BADD_D00045 |
| Description |
The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were not described in literature until the 1940s.[A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and [regadenson].[A229833,A229838] Adenosine is also indicated in the treatment of supraventricular tachycardia.[L31998]
Adenosine was granted FDA approval on 30 October 1989.[L31978] |
| Indications and Usage |
Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy in patients unable to adequately exercise.[L31983] It is also indicated to convert sinus rhythm of paroxysmal supraventricular tachycardia.[L31998] |
| Marketing Status |
approved; investigational |
| ATC Code |
C01EB10 |
| DrugBank ID |
DB00640
|
| KEGG ID |
D00045
|
| MeSH ID |
D000241
|
| PubChem ID |
60961
|
| TTD Drug ID |
D06IAR
|
| NDC Product Code |
73590-0037; 73590-0051; 73590-0081; 81758-010; 82083-0008; 82879-0001; 14593-933; 17478-953; 51662-1631; 55150-192; 73590-0034; 73590-0035; 73590-0080; 82083-0007; 17478-542; 71872-7209; 82083-0012; 82083-0018; 82083-0021; 82428-030; 82879-0002; 82879-0003; 0409-1932; 71080-0027; 71872-7099; 67457-857; 71872-7035; 72371-010; 73590-0032; 12562-3021; 25021-318; 51662-1632; 67457-855; 67457-859; 71080-0024; 72078-033; 0641-6113; 73509-020; 73590-0036; 73590-0039; 73590-0079; 58623-0061; 51662-1345; 51662-1450; 67457-856; 68083-156; 72211-004; 73509-010; 73590-0033; 82083-0011; 52584-026; 63323-651; 71759-090; 72371-020; 81689-040; 82428-010; 82879-0005; 23155-258; 42491-1200; 0404-9809; 67457-854; 68083-101; 73509-090; 73590-0048; 17478-544; 51662-1511; 62041-300; 67457-858; 68083-157; 73590-0031; 73590-0040; 73590-0076; 73590-0077; 82083-0009; 16714-556; 25021-301; 42491-1100; 62041-290; 73590-0038; 73590-0054; 73590-0078; 16714-997; 55150-193 |
| UNII |
K72T3FS567
|
| Synonyms |
Adenosine | Adenocard | Adenoscan |
|
| Chemical Information |
| Molecular Formula |
C10H13N5O4 |
| CAS Registry Number |
5536-17-4 |
| SMILES |
C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N |
| Chemical Structure |
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| ADRs Induced by Drug |
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