Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Acitretin
Drug ID BADD_D00036
Description An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Indications and Usage For the treatment of severe psoriasis in adults.
Marketing Status approved
ATC Code D05BB02
DrugBank ID DB00459
KEGG ID D02754
MeSH ID D017255
PubChem ID 5284513
TTD Drug ID D05QDC
NDC Product Code 17337-0003; 59981-011; 0093-1136; 0115-1752; 42291-087; 62147-0145; 0115-1751; 42794-081; 0378-7020; 71214-0698; 42291-088; 58159-058; 71052-692; 0115-1753; 17337-0004; 71214-0667; 0115-1750; 71214-0668; 71214-0669; 42291-086; 42794-080; 0093-1135; 0093-1138; 62147-0146; 76055-0001; 42794-083; 0378-7023
UNII LCH760E9T7
Synonyms Acitretin | Etretin | Isoacitretin | Isoetretin | Ro 10-1670 | Ro 101670 | Ro-10-1670 | Ro101670 | 13-cis-Acitretin | Neotigason | Soriatane | Acitretin, (Z,E,E,E)-Isomer | Ro-13-7652 | Ro137652 | Ro 13-7652 | Ro 137652
Chemical Information
Molecular Formula C21H26O3
CAS Registry Number 55079-83-9
SMILES CC1=CC(=C(C(=C1C=CC(=CC=CC(=CC(=O)O)C)C)C)C)OC
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood albumin decreased13.09.01.001---
Blood albumin increased13.09.01.002---
Blood bilirubin increased13.03.04.018--
Blood calcium decreased13.11.01.002---
Blood calcium increased13.11.01.003---
Blood chloride decreased13.11.01.004---
Blood chloride increased13.11.01.005---
Blood cholesterol increased13.12.01.002--
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine increased13.13.01.004--
Blood glucose decreased13.02.02.001---
Blood glucose increased13.02.02.002---
Blood iron decreased13.11.01.006---
Blood iron increased13.11.01.007---
Blood lactate dehydrogenase increased13.04.02.002--
Blood magnesium decreased13.11.01.008---
Blood magnesium increased13.11.01.009---
Blood potassium decreased13.11.01.010---
Blood potassium increased13.11.01.011---
Blood sodium decreased13.11.01.012---
Blood sodium increased13.11.01.013---
Blood triglycerides increased13.12.03.001---
Blood urea increased13.13.01.006---
Blood uric acid increased13.02.04.001---
Body temperature increased13.15.01.001---
Bone disorder15.02.04.004---
Bone pain15.02.01.001--
Bowen's disease16.03.02.004; 23.08.02.0040.001875%-
Bradycardia02.03.02.0020.002499%-
Breast cancer16.10.01.001; 21.05.01.003---
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ADReCS-Target
Drug Name ADR Term Target
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