Drug Name |
Acenocoumarol |
Drug ID |
BADD_D00022 |
Description |
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation.[A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients on acenocoumarol are prohibited from giving blood. |
Indications and Usage |
For the treatment and prevention of thromboembolic diseases. More specifically, it is indicated for the prevention of cerebral embolism, deep vein thrombosis, pulmonary embolism, thromboembolism in infarction and transient ischemic attacks. It is used for the treatment of deep vein thrombosis and myocardial infarction. |
Marketing Status |
approved; investigational |
ATC Code |
B01AA07 |
DrugBank ID |
DB01418
|
KEGG ID |
D07064
|
MeSH ID |
D000074
|
PubChem ID |
54676537
|
TTD Drug ID |
D05HFY
|
NDC Product Code |
Not Available |
UNII |
I6WP63U32H
|
Synonyms |
Acenocoumarol | Nicoumalone | Acenocoumarin | Sinthrome | Synthrom | Syncoumar | Syncumar | Sinkumar | Sintrom | Mini-Sintrom | Mini Sintrom | MiniSintrom |