Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acebutolol hydrochloride
Drug ID BADD_D00020
Description A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Indications and Usage For the management of hypertension and ventricular premature beats in adults.
Marketing Status Prescription; Discontinued
ATC Code C07AB04
DrugBank ID DB01193
KEGG ID D00597
MeSH ID D000070
PubChem ID 441307
TTD Drug ID D0HD9K
NDC Product Code 53746-670; 10135-630; 52932-0719; 65162-670; 51927-2906; 50268-050; 65162-669; 68069-0009; 58159-081; 10135-631; 53746-669
Synonyms Acebutolol | Acetobutolol | Acebutolol Hydrochloride | M&B-17803 A | M&B 17803 A | M&B17803 A | M & B 17803A | Neptal | Prent | Rhotral | Sectral | Monitan | Apo-Acebutolol | Apo Acebutolol | ApoAcebutolol | Novo-Acebutolol | Novo Acebutolol | NovoAcebutolol
Chemical Information
Molecular Formula C18H29ClN2O4
CAS Registry Number 34381-68-5
SMILES CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C.Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eye pain06.08.03.002--
Fatigue08.01.01.002--
Flatulence07.01.04.002--
Headache17.14.01.001--
Hypoaesthesia17.02.06.023--Not Available
Hypotension24.06.03.002--
Insomnia17.15.03.002; 19.02.01.002--
Laryngospasm22.04.02.002--
Malaise08.01.01.003--
Mesenteric artery thrombosis07.15.02.008; 24.01.08.003--Not Available
Micturition disorder20.02.02.005--Not Available
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nocturia20.02.03.001--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Peyronie's disease21.12.01.002--Not Available
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Pruritus23.03.12.001--
Psychomotor hyperactivity17.01.02.011; 19.11.02.003--Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash erythematous23.03.06.003--Not Available
Respiratory distress22.02.01.012--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Systemic lupus erythematosus10.04.03.004; 15.06.02.003; 23.03.02.006--Not Available
Thrombocytopenic purpura01.08.01.003; 23.06.01.007--Not Available
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Wheezing22.03.01.009--
Performance status decreased08.01.03.042--Not Available
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