Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acebutolol
Drug ID BADD_D00019
Description A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Indications and Usage For the management of hypertension and ventricular premature beats in adults.
Marketing Status Prescription; Discontinued
ATC Code C07AB04
DrugBank ID DB01193
KEGG ID D02338
MeSH ID D000070
PubChem ID 1978
TTD Drug ID D0HD9K
NDC Product Code Not Available
Synonyms Acebutolol | Acetobutolol | Acebutolol Hydrochloride | M&B-17803 A | M&B 17803 A | M&B17803 A | M & B 17803A | Neptal | Prent | Rhotral | Sectral | Monitan | Apo-Acebutolol | Apo Acebutolol | ApoAcebutolol | Novo-Acebutolol | Novo Acebutolol | NovoAcebutolol
Chemical Information
Molecular Formula C18H28N2O4
CAS Registry Number 37517-30-9
SMILES CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
Vision blurred06.02.06.007; 17.17.01.010--
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Weight increased13.15.01.006--
Wheezing22.03.01.009--
Xerosis08.01.03.016--Not Available
Lupus-like syndrome10.04.03.003; 15.06.02.004; 23.03.02.004--Not Available
Eye pruritus06.04.05.006--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Affect lability19.04.01.001--Not Available
Dermatitis psoriasiform23.03.14.004--Not Available
Angiopathy24.03.02.007--Not Available
Hot flush08.01.03.027; 21.02.02.001; 24.03.01.005--
Connective tissue disorder15.06.01.006--Not Available
Mediastinal disorder22.09.03.001--Not Available
Decreased appetite08.01.09.028; 14.03.01.005--
Erectile dysfunction19.08.04.001; 21.03.01.007--
Ill-defined disorder08.01.03.049--Not Available
Psychotic disorder19.03.01.002--
Oropharyngeal discomfort07.05.05.008; 22.02.05.027--Not Available
Oropharyngeal pain07.05.05.004; 22.02.05.022--
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ADReCS-Target
Drug Name ADR Term Target
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