Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acebutolol
Drug ID BADD_D00019
Description A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Indications and Usage For the management of hypertension and ventricular premature beats in adults.
Marketing Status Prescription; Discontinued
ATC Code C07AB04
DrugBank ID DB01193
KEGG ID D02338
MeSH ID D000070
PubChem ID 1978
TTD Drug ID D0HD9K
NDC Product Code Not Available
Synonyms Acebutolol | Acetobutolol | Acebutolol Hydrochloride | M&B-17803 A | M&B 17803 A | M&B17803 A | M & B 17803A | Neptal | Prent | Rhotral | Sectral | Monitan | Apo-Acebutolol | Apo Acebutolol | ApoAcebutolol | Novo-Acebutolol | Novo Acebutolol | NovoAcebutolol
Chemical Information
Molecular Formula C18H28N2O4
CAS Registry Number 37517-30-9
SMILES CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Menopausal symptoms21.02.02.002--Not Available
Mood swings19.04.03.001--Not Available
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Nocturia20.02.03.001--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Orthostatic hypotension17.05.01.020; 24.06.03.004--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Palpitations02.01.02.003--
Paraesthesia17.02.06.005--
Peripheral coldness08.01.09.010; 24.04.03.006--Not Available
Peyronie's disease21.12.01.002--Not Available
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Pleuritic pain22.02.04.008--
Pneumonia11.01.09.003; 22.07.01.003--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rash erythematous23.03.06.003--Not Available
Respiratory distress22.02.01.012--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Shock24.06.02.002--Not Available
Sinus arrest02.03.03.007--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Syncope02.01.02.008; 17.02.04.008; 24.06.02.012--
Systemic lupus erythematosus10.04.03.004; 15.06.02.003; 23.03.02.006--Not Available
Thrombocytopenic purpura01.08.01.003; 23.06.01.007--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
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ADReCS-Target
Drug Name ADR Term Target
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